Table 10 Performance of LPA test as compared to DST in detecting Isoniazid (INH) resistance
Sensitivity | Specificity | Predictive values | Kappa | ||
|---|---|---|---|---|---|
Positive | Negative | ||||
KatG | 66.7 (34.9–90.1) | 97.2 (92.0–99.4) | 72.7 (44.9–89.7) | 96.3 (92.1–98.3%) | 0.663 (P < 0.01) |
inhA | 25.0 (5.5–57.19) | 98.1 (93.4–99.8) | 60 (21.7–89.01) | 92.11 (89.4–94.2) | 0.319 (P < 0.01) |
KatG and inhA | 91.7 (61.5–99.8) | 95.33 (89.4–98.5) | 68.8 (47.9–84.4) | 99.0 (94.0–99.9) | 0.758 (p < 0.01) |