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Table 2 Baseline data of included studies

From: Accumulate evidence for IP-10 in diagnosing pulmonary tuberculosis

Author IP-10 method IP-10 condition HIV-infection Sensitivity (%) Specificity (%) TP FP FN TN
Zhao Y [7] multiplex cytokines assay unstimulated no 90.9 100 30 0 3 8
Zhao Y [7] two cytokines assay unstimulated no 90.14 86.21 192 4 21 25
Zhao Y [7] two cytokines assay unstimulated no 60.45 100 81 0 53 40
Blauenfeldt T [13] ELISA stimulated (TB Ag) some 82 97 53 5 12 155
Jacobs R [14] multiplex cytokines assay unstimulated some 86 73 19 9 3 24
Lee K [15] ELISA unstimulated no 70.1 88.3 141 30 60 226
Azab NY [16] ELISA stimulated (TB Ag) no 100 60 10 8 0 12
Wang X [17] multiplex cytokines assay stimulated (TB Ag) no 86 85.9 153 22 25 134
Hong JY [18] ELISA stimulated (TB Ag) no 97.8 87.5 45 4 1 28
Hong JY [18] ELISA unstimulated no 87.5 90.5 21 2 3 19
Kabeer BSA [19] ELISA stimulated (TB Ag) no 91.4 48 160 52 15 48
Luo J [20] multiplex cytokine assay unstimulated no 86 57.14 43 21 7 28
Manna MPL [21] multiplex cytokine assay stimulated (TB Ag-nil) no 80.77 85 21 3 5 17
Balcells ME [22] multiplex cytokine assay stimulated (TB Ag-nil) no 44.1 88.9 15 3 19 24
Nonghanphithak D [23] ELISA stimulated (TB Ag) no 79.2 87.2 38 5 10 34
Nonghanphithak D [23] ELISA unstimulated no 95.8 94.9 46 2 2 37
Nonghanphithak D [23] ELISA stimulated (TB Ag-nil) no 58.3 97.4 28 1 20 38
Biraro IA [24] ELISA stimulated (TB Ag) some 83.3 84.9 85 10 17 56
Biraro IA [24] ELISA stimulated (TB Ag/mitogen ratio) some 96.7 78.7 99 14 3 52
Wergeland I [25] multiplex cytokines assay unstimulated yes 100 92.3 6 4 0 48
Petrone L [26] ELISA unstimulated no 79 93.9 15 2 4 31
Latorre I [27] ELISA stimulated (TB Ag) no 66.7 76.7 8 32 4 105
Wang S [28] ELISA stimulated (TB Ag) no 89.4 81.6 59 14 7 62
Jeong YH [29] multiplex cytokines assay stimulated (TB Ag/mitogen ratio) no 93.9 100 31 0 2 26
  1. Abbreviations: IP-10 Interferon gamma-induced protein 10, ELISA Enzyme-linked immuno sorbent assay, TB Ag M. tuberculosis-specific antigens, TB Ag-nil MTB-specific antigen stimulated minus unstimulated levels, TP True positive, FP False positive, FN False negative, TN True negative