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Table 2 Baseline data of included studies

From: Accumulate evidence for IP-10 in diagnosing pulmonary tuberculosis

Author

IP-10 method

IP-10 condition

HIV-infection

Sensitivity (%)

Specificity (%)

TP

FP

FN

TN

Zhao Y [7]

multiplex cytokines assay

unstimulated

no

90.9

100

30

0

3

8

Zhao Y [7]

two cytokines assay

unstimulated

no

90.14

86.21

192

4

21

25

Zhao Y [7]

two cytokines assay

unstimulated

no

60.45

100

81

0

53

40

Blauenfeldt T [13]

ELISA

stimulated (TB Ag)

some

82

97

53

5

12

155

Jacobs R [14]

multiplex cytokines assay

unstimulated

some

86

73

19

9

3

24

Lee K [15]

ELISA

unstimulated

no

70.1

88.3

141

30

60

226

Azab NY [16]

ELISA

stimulated (TB Ag)

no

100

60

10

8

0

12

Wang X [17]

multiplex cytokines assay

stimulated (TB Ag)

no

86

85.9

153

22

25

134

Hong JY [18]

ELISA

stimulated (TB Ag)

no

97.8

87.5

45

4

1

28

Hong JY [18]

ELISA

unstimulated

no

87.5

90.5

21

2

3

19

Kabeer BSA [19]

ELISA

stimulated (TB Ag)

no

91.4

48

160

52

15

48

Luo J [20]

multiplex cytokine assay

unstimulated

no

86

57.14

43

21

7

28

Manna MPL [21]

multiplex cytokine assay

stimulated (TB Ag-nil)

no

80.77

85

21

3

5

17

Balcells ME [22]

multiplex cytokine assay

stimulated (TB Ag-nil)

no

44.1

88.9

15

3

19

24

Nonghanphithak D [23]

ELISA

stimulated (TB Ag)

no

79.2

87.2

38

5

10

34

Nonghanphithak D [23]

ELISA

unstimulated

no

95.8

94.9

46

2

2

37

Nonghanphithak D [23]

ELISA

stimulated (TB Ag-nil)

no

58.3

97.4

28

1

20

38

Biraro IA [24]

ELISA

stimulated (TB Ag)

some

83.3

84.9

85

10

17

56

Biraro IA [24]

ELISA

stimulated (TB Ag/mitogen ratio)

some

96.7

78.7

99

14

3

52

Wergeland I [25]

multiplex cytokines assay

unstimulated

yes

100

92.3

6

4

0

48

Petrone L [26]

ELISA

unstimulated

no

79

93.9

15

2

4

31

Latorre I [27]

ELISA

stimulated (TB Ag)

no

66.7

76.7

8

32

4

105

Wang S [28]

ELISA

stimulated (TB Ag)

no

89.4

81.6

59

14

7

62

Jeong YH [29]

multiplex cytokines assay

stimulated (TB Ag/mitogen ratio)

no

93.9

100

31

0

2

26

  1. Abbreviations: IP-10 Interferon gamma-induced protein 10, ELISA Enzyme-linked immuno sorbent assay, TB Ag M. tuberculosis-specific antigens, TB Ag-nil MTB-specific antigen stimulated minus unstimulated levels, TP True positive, FP False positive, FN False negative, TN True negative