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Table 1 The main characteristics of included studies

From: Accumulate evidence for IP-10 in diagnosing pulmonary tuberculosis

Author

Year

Country

TB high-burden country

Study design

Age

Number of participants

TB site

Non-TB status

IP-10 cut-off

Reference standard

Zhao Y [7]

2018

China

yes

prospective cohort

children and adult

41

PTB

healthy controls

not report

A, B

Zhao Y [7]

2018

China

yes

prospective cohort

children and adult

242

PTB

healthy controls

not report

A, B

Zhao Y [7]

2018

China

yes

prospective cohort

children and adult

174

PTB

healthy controls

not report

A, B

Blauenfeldt T [13]

2016

Denmark

no

prospective cohort

adult

225

PTB

healthy controls

2300 pg/ml

B

Jacobs R [14]

2016

South Africa

yes

prospective cohort

adult

55

PTB

non-TB controls (other respiratory diseases)

>  746.6 pg/ml

B

Lee K [15]

2015

Republic of Korea

no

cross-sectional

adult

457

PTB

healthy controls

68.5 pg/ml

A

Azab NY [16]

2013

Egypt

no

prospective cohort

adult

30

PTB

healthy controls

not report

B

Wang X [17]

2012

China

yes

cross-sectional

adult

334

PTB

healthy controls

589 pg/ml

A, B/C

Hong JY [18]

2012

Republic of Korea

no

cross-sectional

adult

78

PTB

healthy controls

2811/119.5 pg/ml

A, B

Kabeer BSA [19]

2012

India

yes

retrospective case control

adult

277

PTB

healthy controls

not report

A, B

Luo J [20]

2018

China

yes

prospective cohort

adult

100

PTB

healthy controls

631.4 pg/ml

A, B

Manna MPL [21]

2018

Italy

no

retrospective cohort

children and adult

47

PTB

non-TB controls (other non-TB pulmonary infections)

>  6557 pg/ml

A, D

Balcells ME [22]

2018

Chile

no

prospective cohort

children and adult

61

PTB

household contacts (QFT -)

>  42.6 pg/ml

A, B

Nonghanphithak D [23]

2017

Thailand

yes

prospective cohort

adult

87

PTB

healthy controls

6319, 2372, 6964 pg/ml

A, B, D

Biraro IA [24]

2015

Uganda

yes

prospective cohort

children and adult

168

PTB

household contacts (TST and QFT -)

4858 pg/ml, 0.47

A

Wergeland I [25]

2015

Norway

no

prospective cohort

adult

58

PTB

non-TB controls (HIV-infected)

2532 pg/ml

A, B

Petrone L [26]

2015

Uganda

yes

prospective cohort

children

52

PTB

healthy controls

209.1 pg/ml

A, B

Latorre I [27]

2014

Spain

no

retrospective cohort

children

149

PTB

healthy controls

2400 pg/ml

A

Wang S [28]

2012

China

yes

cross-sectional

children and adult

142

PTB

healthy controls

451.3 pg/ml

A, B

Jeong YH [29]

2015

Republic of Korea

no

cross-sectional

adult

59

PTB

healthy controls

0.7906

A, C

  1. Abbreviations: TB Tuberculosis, PTB Pulmonary tuberculosis, QFT QuantiFERON-TB gold test, TST Tuberculin skin test, HIV Human immunodeficiency virus, IP-10 Interferon gamma-induced protein 10, A MTB positive cultures, B Sputum smear microscopy and/or acid-fast bacilli (AFB) positive, C Pathological examination, D Genexpert MTB/RIF