TY - JOUR AU - Liu, Guangjie AU - Li, Youjia AU - Qin, Li AU - Yan, Yongxiang AU - Ye, Yijian AU - Chen, Yue AU - Huang, Cuizhu AU - Zhao, Siting AU - Yao, Yongchao AU - Su, Zhong AU - Chen, Xiaoping PY - 2019 DA - 2019/11/12 TI - SIV infection aggravates malaria in a Chinese rhesus monkey coinfection model JO - BMC Infectious Diseases SP - 965 VL - 19 IS - 1 AB - The co-occurrence of human immunodeficiency virus (HIV) infection and malaria in humans in endemic areas raises the question of whether one of these infections affects the course of the other. Although epidemiological studies have shown the impact of HIV infection on malaria, the mechanism(s) are not yet fully understood. Using a Chinese rhesus macaque coinfection model with simian immunodeficiency virus (SIV) and Plasmodium cynomolgi (Pc) malaria, we investigated the effect of concurrent SIV infection on the course of malaria and the underlying immunological mechanism(s). SN - 1471-2334 UR - https://doi.org/10.1186/s12879-019-4465-6 DO - 10.1186/s12879-019-4465-6 ID - Liu2019 ER -