Skip to main content

Table 3 Diagnostic Accuracy of Different Methods for Prediction of Liver Fibrosis

From: The liver fibrosis index is superior to the APRI and FIB-4 for predicting liver fibrosis in chronic hepatitis B patients in China

 

Optimized cut off value

Sensitivity (%)

Specificity (%)

AUC (95%CI)

P value of ROC contrast test

F0-F1 vs. F2-F4

 APRI

0.58

62.38

71.29

0.73 (0.63, 0.76)

< 0.001

 FIB-4

4.68

60.63

65.56

0.74 (0.68, 0.80)

< 0.001

 LFI

2.61

81.62

80.47

0.77 (0.69, 0.82)

< 0.001

F0-F2vs.F3-F4

 APRI

1.53

62.65

70.26

0.70 (0.63, 0.74)

< 0.001

 FIB-4

5.76

64.48

63.19

0.70 (0.66, 0.71)

0.001

 LFI

3.20

69.82

74.26

0.73 (0.65, 0.77)

< 0.001

F0-F3 vs. F4

 APRI

2.07

60.73

62. 68

0.75 (0.69, 0.84)

< 0.001

 FIB-4

7.83

59.08

58.83

0.76 (0.66, 0.79)

< 0.001

 LFI

3.92

82.29

83.71

0.79 (0.70, 0.88)

< 0.001

  1. Optimized cut off value: were chosen by Youden Index which was the optimal combination of sensitivity and specificity, APRI aspartate aminotransferase-to-platelet ratio index, FIB-4 fibrosis index based on four factors, LFI liver fibrosis index