The liver fibrosis index is superior to the APRI and FIB-4 for predicting liver fibrosis in chronic hepatitis B patients in China

Table 2 Patient characteristics according to the Scheuer fibrosis stage

Characteristic	F0(n = 12)^*	F1(n = 18)	F2(n = 21)	F3(n = 19)	F4(n = 21)	P
Age (year)	32.25 ± 10.36	38.17 ± 10.99	40.90 ± 11.45	43.68 ± 12.37	46.33 ± 13.46	0.018
Male/female^§	7/5	9/9	12/9	10/9	11/10	0.988^#
ALT (IU/L)	60.67 ± 17.84	83.22 ± 54.43	83.30 ± 57.13	94.21 ± 74.63	105.35 ± 75.36	0.345
AST (IU/L)	35.58 ± 16.22	35.08 ± 21.16	41.46 ± 26.34	52.58 ± 38.82	60.18 ± 39.41	0.066
GGT (IU/L)	46.50 ± 32.95	55.53 ± 38.34	90.49 ± 53.86	104.32 ± 99.57	136.96 ± 110.49	0.006
PLT (10⁹/L)	254.08 ± 72.08	194.50 ± 50.08	182.76 ± 47.16	159.42 ± 79.28	107.33 ± 40.92	< 0.001

Data are presented as the mean ± standard deviation and analysed by analysis of variance (ANOVA) unless indicated. ALT alanine aminotransferase, AST aspartate aminotransferase, GGT gamma-glutamyl transpeptidase, PLT platelet count, APRI aspartate aminotransferase-to-platelet ratio index, FIB-4 fibrosis index based on four factors, LFI liver fibrosis index. ^*Number in each fibrosis stage. ^§Number of males and females. ^#Chi-square test

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