From: Cognitive impairments in patients with persistent symptoms attributed to Lyme disease
Characteristic | Good performance validity (n = 239) | Poor performance validity (n = 40) | P Value |
---|---|---|---|
Women, no. (%) | 109 (45.6) | 19 (47.5) | 0.82 |
Education level, no. (%) | |||
Low (≤8 years) | 1 (0.4) | 0 (0) | 0.03 |
Average (9–11 years) | 125 (52.7) | 28 (71.8) | |
High (≥12 years) | 111 (46.8) | 11 (28.2) | |
Paid work, no. (%) | 154 (64.7) | 17 (43.6) | 0.01 |
Age, mean (± SD), years | 48.7 (11.9) | 49.0 (11.9) | 0.87 |
Duration of symptoms, median (IQR), years | 2.7 (1.3–6.3) | 1.8 (0.7–5.7) | 0.13 |
Previous antibiotic treatment for Lyme disease, no. (%) | 213 (89,1) | 33 (82.5) | 0.23 |
Delay symptom onset and treatment, median (IQR), weeks | 22.5 (3.0–103.5) | 15.5 (2.0–69.0) | 0.41 |
History of meningoradiculitis (neuroborreliosis), no. (%)c | 18 (7.5) | 3 (7.7) | 0.97 |
CFQ, mean (95% CI) | |||
Orientation | 3.92 (3.65–4.18) | 4.98 (4.20–5.75) | 0.004b |
Distractibility | 11.29 (10.71–11.87) | 12.98 (11.58–14.37) | 0.03 |
Blunders | 7.04 (6.70–7.38) | 7.95 (7.15–8.75) | 0.05 |
Memory | 7.32 (7.05–7.59) | 7.03 (6.28–7.77) | 0.43 |
Total | 43.23 (41.52–44.94) | 47.73 (43.24–52.21) | 0.05 |
HADS, mean (95% CI) | |||
Anxiety | 6.36 (5.82–6.90) | 6.08 (4.90–7.26) | 0.71 |
Depression | 7.47 (6.98–7.96) | 8.76 (7.33–10.19) | 0.06 |
CIS, mean (95% CI) | |||
Fatigue severity | 43.62 (42.33–44.91) | 47.25 (44.38–50.11) | 0.03 |
Concentration | 23.84 (22.92–24.76) | 25.35 (22.74–27.96) | 0.23 |
Motivation | 16.67 (15.92–17.42) | 17.93 (15.93–19.92) | 0.22 |
Activity | 13.92 (13.27–14.57) | 16.15 (14.73–17.57) | 0.01b |
Total | 98.03 (95.34–100.72) | 106.65 (100.82–112.49) | 0.02 |
Self-efficacy, mean (95% CI) | 17.28 (16.60–17.96) | 15.62 (13.92–17.31) | 0.07 |
ICQ, mean (95% CI) | |||
Helplessness | 13.26 (12.71–13.80) | 15.54 (14.20–16.87) | 0.002b |
Acceptance | 13.68 (13.17–14.20) | 13.42 (12.27–14.58) | 0.70 |
Perceived benefits | 11.35 (10.82–11.88) | 12.63 (11.43–13.82) | 0.07 |
EPQ, mean (95% CI) | |||
Neuroticism | 8.27 (7.59–8.96) | 7.67 (6.22–9.12) | 0.50 |
Extraversion | 11.44 (10.83–12.04) | 12.21 (10.60–13.81) | 0.34 |
PSWQ, mean (95% CI) | 42.17 (40.55–43.78) | 42.15 (38.30–46.00) | 0.99 |
BSQ, mean (95% CI) | 2.27 (2.19–2.35) | 2.38 (2.17–2.59) | 0.33 |