Self-reported antiretroviral therapy adherence and viral load in criminal justice-involved populations

BMC Infectious Diseases

Table 5 Associations of Adherence^d with Log- viral load, Stratified by ART Type among Criminal Justice-Involved (STTR) and Routine Clinical Care (CNICS) Study Samples^a

	Mean VAS^c	Coeff	95% CI	P-value	Interaction P-value¹
STTR N = 234^b
STTR Overall	87	−0.17	− 0.37,0.03	0.09	NA
NNRTI (n = 72)	86	−0.16	−0.47, 0.14	0.30	Ref
PI (n = 125)	89	−0.21	−0.52, 0.10	0.18	0.82
INSTI (n = 12)	87	0.55	−0.43, 1.53	0.27	0.17
Other/Combo (n = 25)	78	−0.31	−0.77, 0.14	0.18	0.60
CNICS N = 11,698
CNICS Overall	92	−0.42	−0.45, − 0.38	< 0.001	NA
NNRTI (n = 3347)	94	− 0.28	− 0.35, − 0.21	< 0.001	Ref
PI (n = 2979)	90	− 0.42	−0.49, − 0.35	< 0.001	0.004
INSTI (n = 2626)	93	− 0.35	− 0.42, − 0.27	< 0.001	0.20
Combination/Other (n = 2746)	91	− 0.51	−0.58, − 0.43	< 0.001	< 0.001

¹Interaction P-value for the test of whether the regression coefficient for the given ART type is different than that for NNRTI
^aLinear regressions of Log VL on adherence, adjusted for age, sex, and study indicator, stratified by ART type in the criminal justice and routine care samples
^bn = 180 had missing ART type
^cMean VAS was not significantly different by regimen in STTR (p = 0.08), and was significantly different by regimen in CNICS (p < 0.001)
^dAdherence measured in 10% increments of the VAS

ISSN: 1471-2334