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Table 3 Assay performance simulating high-volume CT/NG testing (n = 556), results for Neisseria gonorrhoeae*

From: High-volume workflow and performance comparisons for Chlamydia trachomatis and Neisseria gonorrhoeae testing using automated molecular platforms

 

Aptima Combo 2

 

NG positive

NG negative

Total

cobas CT/NG

NG positive

4

1

5

NG negative

0

551

551

Total

4

552

556

PPA (95% CI), NPA (95% CI)

100 (39.8, 100)

99.8 (99, 100)

 

OPA (95% CI)

99.8 (99, 100)

  

p-value

1

  
  1. *Comparison of cobas CT/NG for use on the cobas 6800 system and Aptima Combo 2 on the Panther system
  2. Calculated using McNemar’s test
  3. Abbreviations: CI confidence interval, NG Neisseria gonorrhoeae, NPA negative percent agreement, OPA overall percent agreement, PPA positive percent agreement