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Table 3 Colonisation with lactobacilli: number of women colonised and frequency of isolation during follow-up

From: An exploratory pilot study evaluating the supplementation of standard antibiotic therapy with probiotic lactobacilli in south African women with bacterial vaginosis

Group Colonisation and isolation frequency of probiotic strains and other lactobacilli
Group Women colonised P-valuea Frequency of isolation (%)b P-valuea
Either of the probiotic strains Group 1 5/13 (39%)   12/75 (16%)  
Group 2 10/12 (83%) p = 0.041 (vs Gr. 1)* 25/69 (36%) p  = 0.007 (vs Gr. 1)*
Group 3 0/14 (0%) p = 0.0159 (vs Gr. 1)* 0/71 (0%) p  = 0.0003 (vs Gr. 1)*
p = 0.0001 (vs Gr. 2)* p  < 0.0001 (vs Gr. 2)*
L. rhamnosus Group 1 3/13 (23%)   10/75 (13%)  
Group 2 9/12 (75%) p = 0.017 (vs Gr. 1)* 21/69 (30%) p = 0.015 (vs Gr. 1)*
Group 3 0/14 (0%) P > 0.05 (vs Gr. 1) 0/71 (0%) p = 0.0015 (vs Gr. 1)*
P = 0.0001 (vs Gr. 2)* p < 0.0001 (vs Gr. 2)*
L. gasseri Group 1 2/13 (15%)   4/75 (5%)  
Group 2 8/12 (67%) p = 0.015 (vs Gr. 1)* 13/69 (19%) p = 0.018 (vs Gr. 1)*
Group 3 0/14 (0%) P > 0.05 (vs Gr. 1) 0/71 (0%) p  > 0.05 (vs Gr. 1)
p = 0.0003 (vs Gr. 2)* p  < 0.0001 (vs Gr. 2)*
Other lactobacilli Group 1 12/13 (92%)   53/75 (71%)  
Group 2 12/12 (100%) p > 0.05 (vs Gr. 1) 39/69 (57%) p > 0.05 (vs Gr. 1)
Group 3 12/14 (86%) p > 0.05 (vs Gr. 1) 35/71 (49%) p = 0.011 (vs Gr. 1)*
p > 0.05 (vs Gr. 2) p > 0.05 (vs Gr. 2)
Any lactobacilli Group 1 13/13 (100%)   59/75 (78%)  
Group 2 12/12 (100%) p > 0.05 (vs Gr. 1) 53/69 (77%) p > 0.05 (vs Gr. 1)
Group 3 12/14 (86%) p > 0.05 (vs Gr. 1) 35/71 (49%) p = 0.0003 (vs Gr. 1)*
p > 0.05 (vs Gr. 2) p = 0.0009 (vs Gr. 2)*
  1. aSignificant difference by Fisher’s exact test (two tailed) indicated by an asterisk (*)
  2. bThe frequency of isolation was determined as the number of samples positive for probiotic strains or other lactobacilli on the total number of samples for each group during the entire follow-up (visits 2-7)