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Table 3 Colonisation with lactobacilli: number of women colonised and frequency of isolation during follow-up

From: An exploratory pilot study evaluating the supplementation of standard antibiotic therapy with probiotic lactobacilli in south African women with bacterial vaginosis

Group

Colonisation and isolation frequency of probiotic strains and other lactobacilli

Group

Women colonised

P-valuea

Frequency of isolation (%)b

P-valuea

Either of the probiotic strains

Group 1

5/13 (39%)

 

12/75 (16%)

 

Group 2

10/12 (83%)

p = 0.041 (vs Gr. 1)*

25/69 (36%)

p  = 0.007 (vs Gr. 1)*

Group 3

0/14 (0%)

p = 0.0159 (vs Gr. 1)*

0/71 (0%)

p  = 0.0003 (vs Gr. 1)*

p = 0.0001 (vs Gr. 2)*

p  < 0.0001 (vs Gr. 2)*

L. rhamnosus

Group 1

3/13 (23%)

 

10/75 (13%)

 

Group 2

9/12 (75%)

p = 0.017 (vs Gr. 1)*

21/69 (30%)

p = 0.015 (vs Gr. 1)*

Group 3

0/14 (0%)

P > 0.05 (vs Gr. 1)

0/71 (0%)

p = 0.0015 (vs Gr. 1)*

P = 0.0001 (vs Gr. 2)*

p < 0.0001 (vs Gr. 2)*

L. gasseri

Group 1

2/13 (15%)

 

4/75 (5%)

 

Group 2

8/12 (67%)

p = 0.015 (vs Gr. 1)*

13/69 (19%)

p = 0.018 (vs Gr. 1)*

Group 3

0/14 (0%)

P > 0.05 (vs Gr. 1)

0/71 (0%)

p  > 0.05 (vs Gr. 1)

p = 0.0003 (vs Gr. 2)*

p  < 0.0001 (vs Gr. 2)*

Other lactobacilli

Group 1

12/13 (92%)

 

53/75 (71%)

 

Group 2

12/12 (100%)

p > 0.05 (vs Gr. 1)

39/69 (57%)

p > 0.05 (vs Gr. 1)

Group 3

12/14 (86%)

p > 0.05 (vs Gr. 1)

35/71 (49%)

p = 0.011 (vs Gr. 1)*

p > 0.05 (vs Gr. 2)

p > 0.05 (vs Gr. 2)

Any lactobacilli

Group 1

13/13 (100%)

 

59/75 (78%)

 

Group 2

12/12 (100%)

p > 0.05 (vs Gr. 1)

53/69 (77%)

p > 0.05 (vs Gr. 1)

Group 3

12/14 (86%)

p > 0.05 (vs Gr. 1)

35/71 (49%)

p = 0.0003 (vs Gr. 1)*

p > 0.05 (vs Gr. 2)

p = 0.0009 (vs Gr. 2)*

  1. aSignificant difference by Fisher’s exact test (two tailed) indicated by an asterisk (*)
  2. bThe frequency of isolation was determined as the number of samples positive for probiotic strains or other lactobacilli on the total number of samples for each group during the entire follow-up (visits 2-7)