Dates | Relevant Past Medical History and Interventions | ||
---|---|---|---|
No particular medical history | |||
Dates | Summaries from Initial and Follow-up Visits | Diagnostic Testing | Interventions |
Day 1 | 5 days history of muti-injury caused by high falling; coma; status after removal of traumatic intracranial hematoma and decompressive craniectomy; fever |
Body temperature: 37.6 °C; Blood pressure: 165/79 mmHg; Glasgow Coma Score: 1 + T + 1; White blood cell count: 17.1 × 10E9/L; Neutrophils%: 90.6%; hsCRP: 209.70 mg/L; PCT: 0.38 ng/ml; pO2: 117 mmHg; pCO2: 31.4 mmHg; X bedside photography: Exudative changes in the left lung, left rib fractures. |
Antibiotic regimen: meropenem 2 g IV, 8 hourly and vancomycin 1million IU IV 12 hourly; Symptomatic treatment |
Day 3 | Left lung infection |
Body temperature: 38.2 °C; Cranial plain CT: Changes after craniocerebral surgery, multiple intracranial hemorrhages, subarachnoid hemorrhage; Lung CT plain scan: Patchy consolidation in left inferior lobar, left rib fractures | |
Day 7 | Patient got better after treatment |
Body temperature: 37.4 °C; White blood cell count: 12.3 × 10E9/L; Neutrophils%: 89.5%; hsCRP: 6.7 mg/L; PCT: 0.12 ng/ml; Blood culture: No bacteria growth after 7 days’ culture | |
Day 8 | Pandoraea Apista was considered as a colonization | Sputum culture: Pandoraea Apista (identified by MALDI-TOF MS) | |
Day 11 | Infection in both lungs; new confirmed infection in right lung |
Body temperature: 38.0 °C; White blood cell count: 20.5 × 10E9/L; Neutrophils%: 95.2%; hsCRP: 194.4 mg/L; Lung CT plain scan: Patchy consolidation in both lungs | |
Day 12 | Physicians got the information from the literature that Pandoraea Apista may be resistant to meropenem but sensitive to imipenem |
Body temperature: 39.2 °C; White blood cell count:22.1 × 10E9/L; Neutrophils%: 93.6%; hsCRP: 260.7 mg/L; pO2: 67.2 mmHg; pCO2: 39.2 mmHg; | Antibiotic regimen changed to imipenem 1 g IV, 6 hourly and vancomycin 1million IU IV 12 hourly |
Day 14 | Patient died |