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Fig. 4 | BMC Infectious Diseases

Fig. 4

From: Echinococcus multilocularis inoculation induces NK cell functional decrease through high expression of NKG2A in C57BL/6 mice

Fig. 4

The peri-parasitic fibrosis in E. multilocularis infected mice while in vivo depletion of NK cells population. a The peri-parasitic fibrosis of hepatic lesion was determined by picric acid-Sirius red staining (the red area represents fibrillar collagen) and immunohistochemical staining for α-SMA (detection of activated hepatic stellate cells) (original magnification× 100). b The peri-parasitic fibrosis area of the section was quantified using cellSens Dimension software, the ratio of collagen area and total area (%) was counted. c The percentage of positive staining cells in peri-parasitic area was calculated using cellSens Dimension software to assess the expression of α-SMA on the lesion around areas. Lesion (*), liver tissue (), peri-parasitic fibrosis area (#), activated hepatic stellate cells (+). (Data were shown as mean ± standard error (SEM, 4 mice per group), *p < 0.05

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