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Table 2 Univariable and multivariable meta-regression models for hepatitis C virus (HCV) prevalence in the general population in Pakistan

From: Characterization of the hepatitis C virus epidemic in Pakistan

 

Number of studies

Univariable analysis

Multivariable analysisa

OR (95% CI)

p-value

Variance explained adjusted R2 (%)

AOR (95% CI)

p-value

General population subpopulations

Blood donors

73

1

–

 

1

–

Pregnant women/ANC attendees

21

2.0 (1.2–3.2)

0.007

 

2.1 (0.5–9.1)

0.324

Non-specific general populations

65

3.3 (2.4–4.6)

< 0.001

 

3.2 (1.6–6.4)

< 0.001

Children

5

0.6 (0.2–1.5)

0.266

 

0.6 (0.2–1.6)

0.299

Outpatients

9

4.8 (2.4–9.7)

< 0.001

 

5.3 (2.1–13.0)

< 0.001

Military personnel

6

0.7 (0.3–1.5)

0.322

 

0.7 (0.3–2.1)

0.572

Refugees

3

2.6 (0.8–8.3)

0.111

26.2

1.9 (0.2–15.6)

0.549

Province

Punjab

64

1

–

 

1

–

Azad Kashmir

3

0.8 (0.2–3.1)

0.735

 

0.7 (0.2–2.5)

0.544

Balochistan

8

1.0 (0.4–2.5)

0.932

 

0.9 (0.4–2.0)

0.856

F.A.T.A

2

0.2 (0.0–0.9)

0.041

 

0.3 (0.1–1.3)

0.099

Islamabad Capital Territory

5

1.2 (0.4–3.5)

0.737

 

1.4 (0.5–4.1)

0.490

Khyber Pakhtunkhwa

30

1.2 (0.7–2.1)

0.397

 

1.0 (0.6–1.7)

0.886

Sindh

58

1.2 (0.8–1.8)

0.488

 

1.3 (0.9–1.8)

0.245

Mixed/Unspecified

12

0.8 (0.8–1.8)

0.560

0.0

1.0 (0.6–2.0)

0.879

Study site

Blood bank

50

1

–

 

1

–

Community

85

2.4 (1.6–3.5)

< 0.001

 

0.9 (0.5–1.9)

0.849

Clinical setting

21

1.5 (0.9–2.7)

0.141

 

0.7 (0.3–1.3)

0.228

ANC clinic

17

2.0 (1.1–3.5)

0.028

 

0.8 (0.2–4.0)

0.777

Refugee camp

2

3.0 (0.6–14.4)

0.178

8.7

1.6 (0.1–19.3)

0.718

Sample size

< 100

8

1

–

 

1

–

≥100

174

0.2 (0.1–0.5)

< 0.001

6.1

0.4 (0.2–0.8)

0.008

Year of data collection

 

182

1.0 (1.0–1.0)

0.413

0.0

–

 

Year of publication

 

182

1.0 (1.0–1.1)

0.565

0.0

–

 
  1. Abbreviations: OR odds ratio, AOR adjusted odds ratio, CI confidence interval, F.A.T.A Federally Administered Tribal Areas, ANC Antenatal Care
  2. aThe adjusted R-squared for the full model was 27.5%