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Table 3 Diagnostic accuracy of presepsin according to the cut off value

From: Presepsin as a diagnostic marker of sepsis in children and adolescents: a systemic review and meta-analysis

 

Number of studies

Sensitivity (95% CI)

Specificity (95% CI)

Positive LR (95% CI)

Negative LR (95% CI)

DOR (95% CI)

AUC

Cutoff ≤650 pg/ml

2

0.84 [0.64, 0.94]

0.42 [0.18, 0.71]

1.45 [0.78, 3.24]

0.38 [0.08, 2.00]

3.81 [1.03, 14.04]

0.827

Cutoff > 650 pg/ml

2

0.99 [0.88, 1.00]

0.90 [0.78, 0.96]

9.9 [4.00, 25.00]

0.01 [0.001, 0.15]

580.75 [73.53, 4586.94]

0.983

  1. CI confidence interval, LR likelihood ratio, DOR diagnostic odds ratio, AUC area under the receiver operating characteristic curve