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Table 4 Comparisons of Clinical characteristics between quinolone-susceptible and quinolone-resistant groups

From: Risk factors for mortality in patients with Stenotrophomonas maltophilia bacteremia and clinical impact of quinolone–resistant strains

Factors

Susceptible group N = 86

Resistant group N = 39

p value

Age, years

63.0 (51.0–70.0)

66.0 (53.5–72.5)

0.215

Age ≥ 65 years, n(%)

37 (43.0)

20 (51.3)

0.390

Gender, male

57 (66.3)

29 (64.6)

0.233

Comorbidities

 HTN

30 (34.9)

16 (41.0)

0.509

 DM

29 (33.7)

10 (25.6)

0.366

 Cardiovascular disease

13 (15.1)

9 (23.1)

0.279

 Chronic kidney disease

6 (7.0)

2 (5.1)

1.000

 End stage renal disease

4 (4.7)

4 (10.3)

0.255

 Chronic liver disease

12 (14.0)

4 (10.3)

0.774

 Pulmonary disease

8 (9.3)

4 (10.3)

1.000

 Solid tumor

42 (48.8)

19 (48.7)

0.990

 Hematologic malignancy

12 (14.0)

6 (15.4)

0.833

 Solid organ transplantation

5 (5.8)

2 (5.1)

1.000

 Charlson score

6.1 ± 3.1

7.4 ± 3.2

0.030

Predisposing factors

 Chemotherapy

11 (12.8)

3 (7.7)

0.546

 Major surgerya

28 (32.9)

16 (35.4)

0.382

 ICU care

54 (62.8)

29 (74.4)

0.205

 Hospital stay before bacteremia, days

17.0 (8.0–34.0)

30.0 (13.5–57.5)

0.015

 Central venous catheter

57 (66.3)

32 (84.2)

0.019

 Hemodialysis catheter

9 (10.5)

8 (21.6)

0.100

 Mechanical ventilator

36 (41.9)

24 (63.2)

0.029

 Foley catheter

47 (54.7)

28 (73.7)

0.046

Clinical findings

 Shock

23 (26.7)

20 (51.3)

0.007

 APACHE II score

13.0 (8.0; 18.0)

14.0 (11.0; 21.5)

0.115

Laboratory findings

 Neutropenia

14 (16.3)

4 (10.3)

0.374

 Hypoalbuminemia

52 (60.5)

21 (53.8)

0.487

 Thrombocytopenia

28 (32.6)

19 (48.7)

0.084

 Hemoglobin, g/L

9.8 ± 1.7

9.4 ± 1.3

0.296

 C-reactive protein, mg/L

86.8 (41.5–142.5)

79.3 (44.5–153.0)

0.914

 Estimated GFR, ml/min per 1.73m2

87.0 (51.0–101.0)

72.0 (45.4–106.0)

0.592

Outcomes

 Inappropriate antimicrobial therapy

23 (26.7)

16 (42.1)

0.089

 Hospital stay, days

50.0 (26.0–78.0)

68.0 (35.0–150.0)

0.054

 Mortality

48 (55.8)

34 (87.2)

0.001

  1. Note. HTN Hypertension, DM Diabetes mellitus, ICU Intensive care unit, APACHE II Acute Physiologic and Chronic Health Evaluation II score
  2. The data were expressed as mean ± standard deviation, number (%), or median (interquartile range)
  3. a Major surgery, any surgical procedure that involves anesthesia or respiratory assistance