Skip to main content

Advertisement

Table 4 Comparisons of Clinical characteristics between quinolone-susceptible and quinolone-resistant groups

From: Risk factors for mortality in patients with Stenotrophomonas maltophilia bacteremia and clinical impact of quinolone–resistant strains

Factors Susceptible group N = 86 Resistant group N = 39 p value
Age, years 63.0 (51.0–70.0) 66.0 (53.5–72.5) 0.215
Age ≥ 65 years, n(%) 37 (43.0) 20 (51.3) 0.390
Gender, male 57 (66.3) 29 (64.6) 0.233
Comorbidities
 HTN 30 (34.9) 16 (41.0) 0.509
 DM 29 (33.7) 10 (25.6) 0.366
 Cardiovascular disease 13 (15.1) 9 (23.1) 0.279
 Chronic kidney disease 6 (7.0) 2 (5.1) 1.000
 End stage renal disease 4 (4.7) 4 (10.3) 0.255
 Chronic liver disease 12 (14.0) 4 (10.3) 0.774
 Pulmonary disease 8 (9.3) 4 (10.3) 1.000
 Solid tumor 42 (48.8) 19 (48.7) 0.990
 Hematologic malignancy 12 (14.0) 6 (15.4) 0.833
 Solid organ transplantation 5 (5.8) 2 (5.1) 1.000
 Charlson score 6.1 ± 3.1 7.4 ± 3.2 0.030
Predisposing factors
 Chemotherapy 11 (12.8) 3 (7.7) 0.546
 Major surgerya 28 (32.9) 16 (35.4) 0.382
 ICU care 54 (62.8) 29 (74.4) 0.205
 Hospital stay before bacteremia, days 17.0 (8.0–34.0) 30.0 (13.5–57.5) 0.015
 Central venous catheter 57 (66.3) 32 (84.2) 0.019
 Hemodialysis catheter 9 (10.5) 8 (21.6) 0.100
 Mechanical ventilator 36 (41.9) 24 (63.2) 0.029
 Foley catheter 47 (54.7) 28 (73.7) 0.046
Clinical findings
 Shock 23 (26.7) 20 (51.3) 0.007
 APACHE II score 13.0 (8.0; 18.0) 14.0 (11.0; 21.5) 0.115
Laboratory findings
 Neutropenia 14 (16.3) 4 (10.3) 0.374
 Hypoalbuminemia 52 (60.5) 21 (53.8) 0.487
 Thrombocytopenia 28 (32.6) 19 (48.7) 0.084
 Hemoglobin, g/L 9.8 ± 1.7 9.4 ± 1.3 0.296
 C-reactive protein, mg/L 86.8 (41.5–142.5) 79.3 (44.5–153.0) 0.914
 Estimated GFR, ml/min per 1.73m2 87.0 (51.0–101.0) 72.0 (45.4–106.0) 0.592
Outcomes
 Inappropriate antimicrobial therapy 23 (26.7) 16 (42.1) 0.089
 Hospital stay, days 50.0 (26.0–78.0) 68.0 (35.0–150.0) 0.054
 Mortality 48 (55.8) 34 (87.2) 0.001
  1. Note. HTN Hypertension, DM Diabetes mellitus, ICU Intensive care unit, APACHE II Acute Physiologic and Chronic Health Evaluation II score
  2. The data were expressed as mean ± standard deviation, number (%), or median (interquartile range)
  3. a Major surgery, any surgical procedure that involves anesthesia or respiratory assistance