Table 1 Baseline characteristics of patients with S. maltophilia bacteremia
Factors | Survivors N = 44 | Non-survivors N = 82 | p value |
|---|---|---|---|
Age, y, mean ± SD | 71.0 (60.5–79) | 74.5 (61.0–80.25) | 0.310 |
Age ≥ 65 years, n(%) | 24 (54.5) | 34 (41.5) | 0.160 |
Male, n (%) | 33 (75.0) | 53 (64.6) | 0.233 |
BMI, kg/m2, median (IQR) | 21.7 (19.4–25.0) | 21.9 (19.0–24.4) | 0.847 |
Comorbidities | |||
HTN, n (%) | 15 (34.1) | 32 (39.0) | 0.585 |
DM, n (%) | 16 (36.4) | 23 (28.0) | 0.336 |
Cardiovascular disease, n (%) | 9 (20.5) | 13 (15.9) | 0.517 |
Chronic kidney diseasea, n (%) | 4 (9.1) | 4 (4.9) | 0.449 |
End stage renal disease, n (%) | 1 (2.3) | 7 (8.5) | 0.259 |
Chronic liver disease, n (%) | 5 (11.4) | 11 (13.4) | 0.742 |
Pulmonary disease, n (%) | 4 (9.1) | 8 (9.8) | 1.000 |
Solid tumor, n (%) | 18 (40.9) | 43 (52.4) | 0.217 |
Hematologic malignancy, n (%) | 1 (2.3) | 17 (20.7) | 0.005 |
Solid organ transplantation, n (%) | 3 (6.8) | 4 (4.9) | 0.694 |
Charlson score, mean ± SD | 5.7 ± 3.0 | 6.9 ± 3.2 | 0.049 |
Predisposing factors | |||
Chemotherapy, n (%) | 4 (9.1) | 10 (12.2) | 0.769 |
Major surgerya, n (%) | 15 (34.9) | 29 (35.4) | 0.957 |
ICU care, n (%) | 29 (65.9) | 54 (65.9) | 0.995 |
Length of stay in hospital before bacteremia (days), median (IQR) | 12.0 (3.5–24.5) | 26.0 (14.0–56.0) | 0.038 |
Central venous catheter, n (%) | 31 (70.5) | 59 (72.8) | 0.777 |
Hemodialysis catheter, n (%) | 2 (4.5) | 15 (18.8) | 0.028 |
Mechanical ventilator, n (%) | 19 (43.2) | 41 (50.6) | 0.427 |
Foley catheter, n (%) | 28 (63.6) | 47 (58.0) | 0.541 |
Clinical severity | |||
Shock, n (%) | 10 (22.7) | 33 (40.2) | 0.075 |
APACHE II score, mean ± SD | 11.0 ± 5.8 | 15.4 ± 6.9 | < 0.001 |
Laboratory findings | |||
Neutropenia, n (%) | 3 (6.8) | 15 (18.3) | 0.079 |
Hypoalbuminemia, n (%) | 18 (6.8) | 56 (18.3) | 0.003 |
Thrombocytopenia, n (%) | 9 (20.5) | 38 (46.3) | 0.004 |
Hemoglobin (g/L), mean ± SD | 10.1 ± 1.6 | 9.4 ± 1.5 | 0.032 |
C-reactive protein (mg/L), median (IQR) | 69.2 (32.2–129.5) | 89.3 (58.5–148.0) | 0.057 |
Estimated GFR (ml/min per 1.73m2), median (IQR) | 85.0 (54.2–98.0) | 80.0 (44.0–104.0) | 0.675 |
Hospital stay, days | 53.0 (20.5–78.0) | 60.0 (35.0–97.0) | 0.137 |
Length of stay in ICU, days | 30 (11.5–50.0) | 39 (23.0–67.0) | 0.640 |