Table 3 Unadjusted and adjusted odds ratios for predictors of persistent high-risk (hr) human papillomavirus (HPV) infection (n = 71)
Predictors of persistence | HrHPV Persistence (n = 31) | HrHPV Clearance (n = 40) | Unadjusted odds ratios | p-value | Adjusted odds ratiosa, b | p-value |
|---|---|---|---|---|---|---|
Age when first hrHPV positive, n(%) | ||||||
≥ 35 years | 22 (44.9) | 27 (55.1) | 1.00 | – | 1.00 | – |
18–34 years | 9 (40.9) | 13 (59.1) | 0.85 (0.31–2.36) | 0.75 | 0.52 (0.13–2.07) | 0.35 |
(missing) | (0) | (0) | ||||
Race, n(%) | ||||||
White | 13 (39.4) | 20 (60.6) | 1.00 | – | 1.00 | – |
Asian | 4 (80.0) | 1 (20.0) | 6.15 (0.62–61.37) | 0.12 | 7.38 (0.68–80.17) | 0.10 |
Black | 14 (45.2) | 17 (54.8) | 1.27 (0.47–3.42) | 0.64 | 1.71 (0.52–5.64) | 0.38 |
(missing) | (0) | (2) | ||||
Combined p-value | 0.30 | 0.22 | ||||
ART duration, (years) | ||||||
Median (IQR) | 5.4 (3.3–11.4) | 8.1 (2.6–12.1) | 0.97 (0.88–1.07) | 0.52 | 0.91 (0.80–1.04) | 0.17 |
(missing) | (1) | (3) | ||||
AIDS prior to inclusion, n(%) | ||||||
No | 21 (38.9) | 33 (61.1) | 1.00 | – | 1.00 | – |
Yes | 10 (62.5) | 6 (37.5) | 2.62 (0.83–8.28) | 0.10 | 3.77 (0.99–14.38) | |
(missing) | (0) | (1) | 0.05 | |||
Smoking status, n(%) | ||||||
Never smoker | 17 (43.6) | 22 (56.4) | 1.00 | – | 1.00 | |
Current smoker/ Ex-smoker | 14 (43.8) | 18 (56.2) | 1.01 (0.39–2.58) | 0.99 | 1.13 (0.35–3.68) | 0.84 |
(missing) | (0) | (0) | ||||
CD4 count when first hrHPV positive (cells/μL), n(%) | ||||||
≥ 350 | 16 (36.4) | 28 (63.6) | 1.00 | – | 1.00 | |
350 | 11 (68.8) | 5 (31.2) | 3.85 (1.13–13.07) | 0.03 | 4.36 (1.18–16.04) | 0.03 |
(missing) | (4) | (7) | ||||