Skip to main content

Table 3 Predictors of Mortality Among HIV-infected and HIV-uninfected Patients in Durban, South Africa

From: Assessing rates and contextual predictors of 5-year mortality among HIV-infected and HIV-uninfected individuals following HIV testing in Durban, South Africa

Measure

Primary analysis

Alternate analyses

PS & CD4 MI

HR (95% CI)

P Ç‚

CD4 MI

HR (95% CI)

PS

HR (95% CI)

Base

HR (95% CI)

a. Adjusted hazard ratio of factors in the primary and alternative multivariable models, and in univariate analyses

 HIV Statusx

3.86 (3.08–4.85)

< 0.001

3.99 (2.94–5.41)

4.44 (3.51–5.62)

4.54 (3.32–6.21)

 Male sex

1.57 (1.35–1.82)

< 0.001

1.67 (1.35–2.06)

1.67 (1.44–1.93)

1.75 (1.41–2.16)

 Test received at primary health clinic

0.51 (0.38–0.68)

< 0.001

0.60 (0.40–0.91)

0.47 (0.35–0.62)

0.55 (0.37–0.83)

 Healthcare use in past year:

  1–2 times

1.53 (1.15–2.02)

0.003

1.66 (1.09–2.54)

1.65 (1.25–2.18)

1.79 (1.17–2.73)

  3–5 times

1.86 (1.41–2.44)

< 0.001

1.99 (1.32–3.00)

2.01 (1.54–2.63)

2.16 (1.44–3.25)

   > 5 times

2.34 (1.75–3.12)

< 0.001

2.39 (1.55–3.67)

2.63 (1.98–3.49)

2.68 (1.75–4.10)

 Total number of healthcare barrier domains reported out of 5 possible

1.12 (1.07–1.16)

< 0.001

1.11 (1.05–1.18)

1.14 (1.09–1.18)

1.13 (1.06–1.20)

 10-point increase in mental health score corresponding to better mental health

0.93 (0.89–0.97)

0.002

0.94 (0.89–1.01)

0.92 (0.88–0.96)

0.94 (0.88–1.00)

 CD4 count (per 100)

0.80 (0.76–0.84)

< 0.001

0.82 (0.76–0.88)

–

–

b. Adjusted hazard ratios related to the interaction between age and HIV status

 10-year age increase for HIV-infected*

1.22 (1.13–1.31)

< 0.001

1.20 (1.07–1.35)

1.24 (1.15–1.34)

1.21 (1.08–1.36)

 10-year age increase for HIV-uninfected*

1.94 (1.78–2.11)

< 0.001

1.89 (1.69–2.11)

1.92 (1.77–2.09)

1.87 (1.67–2.09)

 HR for HIV-infected at age 20

6.59 (4.79–9.06)

< 0.001

6.98 (4.43–11.00)

7.11 (5.07–9.96)

7.24 (4.61–11.38)

 HR for HIV-infected at age 30

4.24 (3.35–5.35)

< 0.001

4.45 (3.18–6.22)

4.59 (3.58–5.89)

4.71 (3.38–6.56)

 HR for HIV-infected at age 40

2.72 (2.26–3.28)

< 0.001

2.83 (2.18–3.67)

2.96 (2.46–3.57)

3.06 (2.38–3.94)

 HR for HIV-infected at age 50

1.75 (1.43–2.15)

< 0.001

1.80 (1.38–2.36)

1.91 (1.60–2.29)

1.99 (1.54–2.57)

 HR for HIV-infected at age 60

1.13 (0.86–1.48)

< 0.001

1.15 (0.81–1.63)

1.24 (0.98–1.56)

1.29 (0.92–1.82)

  1. PS: with propensity score adjustment; CD4 MI: with CD4 multiple imputation; HR: adjusted hazard ratio; Base: baseline analysis without propensity score adjustment or CD4 multiple imputation.
  2. x The HIV status variable is calculated as a contrast based on the parameter estimates for the HIV factor,and age factor, incorporating the average difference in age between the HIV+ and HIV- groups. For models including CD4, the HIV status variable also adjusts for the parameter estimate for CD4 and the and the average difference in CD4 between the HIV+ and HIV- groups
  3. Ç‚ p-values were generated from Cox proportional hazards models
Back to article page

BMC Infectious Diseases

ISSN: 1471-2334

Contact us