Changing face of Candida colonization pattern in pediatric patients with hematological malignancy during repeated hospitalizations, results of a prospective observational study (2016–2017) in shiraz, Iran

Table 7 Colonization characteristics in both studies conducted in AMOC, in children who were colonized with different Candida species

	2017–2018		2011–2012 (18)		p-value ^c
	N ^b	%	N ^b	%	p-value ^c
Candida species ^a
C. Albicans	106	81.6	117	62	0.0003*
C. Krusei	7	5.4	18	9.6	0.2477
C. Parapsilosis	5	3.9	8	4.3	0.9126
C. Glabrata	4	3.1	14	7.5	0.1559
C. Kefyr	4	3.1	4	2.2	0.8893
C. Tropicalis	3	2.4	11	5.9	0.2262
C. Famata	1	0.8	11	5.9	0.0416*
Albicans versus non-Albicans Candida species
Albicans	106	81.6	117	62	0.0003*
Non-Albicans	24	18.5	72	38	0.0003*
Colonization site
Oral	98	75.4	88	38.4	< 0.0001*
Nasal	12	9.2	24	10.4	0.8560
Rectal	20	15.4	77	33.6	0.0003*
Urine	0	0	40	17.4	< 0.0001*

a. Very rare species including C. guilliermondii, C. rugosa, C. Lusitaniae, C. lambica, and Rhodotorula spp. were excluded from 2011 to 2012 study
b. Number of positive samples
c. Chi-square test
*Statistically significant

ISSN: 1471-2334