Table 1 Patient demographics
Baseline variables* | All population (n = 240) | MICU (n = 138) | SICU (n = 102) | p value |
|---|---|---|---|---|
Age, yr | 63.9 ± 14.8 | 62.5 ± 14.7 | 65.9 ± 14.7 | 0.0752 |
BMI | 30.2 ± 9.5 | 30.1 ± 9.3 | 30.4 ± 9.7 | 0.7875 |
Hospital LoS | 19.6 ± 13.3 | 16.5 ± 10.4 | 23.8 ± 15.4 | < 0.0001 |
Duration of MV | 9.1** ± 5.1 | 8.5 ± 5.1 | 9.8** ± 5.1 | 0.0482 |
Male, % (n) | 58.8 (141) | 58.0 (80) | 59.8 (61) | 0.7923 |
All-cause mortality, % (n) | 31.3 (75) | 39.9 (55) | 19.6 (20) | 0.0062 |
SICU, % (n) | 42.5 (102) | N/A | N /A | N/A |
Emergency surgery, % (n) | 30.4 (73) | 8.0 (11) | 60.8 (62) | < 0.0001 |
Trauma, % (n) | 9.2 (22) | 2.9 (4) | 17.6 (18) | 0.0001 |
Hypertension, % (n) | 50.4 (121) | 48.6 (67) | 52.9 (54) | 0.5165 |
Diabetes, % (n) | 27.5 (66) | 29.0 (40) | 25.5 (26) | 0.5627 |
Asthma, % (n) | 7.5 (18) | 8.0 (11) | 6.9 (7) | 0.8088 |
COPD, % (n) | 17.1 (41) | 16.7 (23) | 17.6 (18) | 0.8636 |
Chronic heart failure, % (n) | 16.3 (39) | 19.6 (27) | 11.8 (12) | 0.1146 |
Malignancy, % (n) | 23.8 (57) | 21.0 (29) | 27.5 (28) | 0.2837 |
Previous smoker, % (n) | 26.7 (64) | 26.1 (36) | 27.5 (28) | 0.8829 |
Current smoker, % (n) | 18.3 (44) | 21.7 (30) | 13.7 (14) | 0.1303 |
Alcohol abuse, % (n) | 23.3 (56) | 25.4 (35) | 20.6 (21) | 0.4416 |
Antibiotics in the last 90 days, % (n) | 43.3 (104) | 34.1 (47) | 46.1 (47) | 0.1774 |
Antibiotics upon admission, % (n) | 15.0 (36) | 15.9 (22) | 13.7 (14) | 0.7161 |
Immunoactive drugs***, % (n) | 22.1 (53) | 24.6 (34) | 18.6 (19) | 0.3450 |
Admission due to sepsis, % (n) | 17.1 (41) | 19.6 (27) | 13.7 (14) | 0.2982 |
Admission due to respiratory failure or hypoxia, % (n) | 27.9 (67) | 44.2 (61) | 5.9 (6) | < 0.0001 |
VAP, % (n) | 35.4 (85) | 31.9 (44) | 40.2 (41) | 0.2193 |
S. aureus VAP, % (n) | 7.5 (18) | 5.8 (8) | 9.8 (10) | 1.000 |
Gram-negative VAP, % (n) | 7.5 (18) | 6.5 (9) | 8.8 (9) | 0.6215 |