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Table 5 Comparison of profiles of tuberculosis patients categorized by timing of death using univariate and multivariate analysis

From: Clinical profiles of early and tuberculosis-related mortality in South Korea between 2015 and 2017: a cross-sectional study

Variables Early death (n = 2545) Late death (n = 1190) OR (95% CI) p-value aORa (95% CI) p-value
Age group
  ≤ 49 years 144 (5.7%) 60 (5.0%) 1   1  
 50–59 years 248 (9.7%) 117 (9.8%) 0.88 (0.61–1.28) 0.514 0.96 (0.64–1.44) 0.835
 60–69 years 343 (13.5%) 196 (16.5%) 0.73 (0.52–1.03) 0.076 0.90 (0.61–1.32) 0.577
 70–79 years 711 (27.9%) 347 (29.2%) 0.85 (0.62–1.18) 0.615 0.98 (0.69–1.41) 0.929
 80 years ≤ 1099 (43.2%) 470 (39.5%) 0.97 (0.71–1.34) 0.708 1.01 (0.71–1.44) 0.968
 Female 827 (32.5%) 367 (30.8%) 1.08 (0.93–1.25) 0.312 0.90 (0.75–1.08) 0.238
 Current smokerb 723 (61.6%) 1690 (66.7%) 0.72 (0.62–0.85) 0.000 0.76 (0.59–0.99) 0.039
 Body mass index < 18.5 kg/m2 1030 (42.6%) 412 (35.7%) 1.34 (1.16–1.55) 0.000 1.26 (1.08–1.48) 0.003
Comorbidities
 Diabetes mellitus 321 (27.1%) 626 (24.8%) 0.89 (0.76–1.04) 0.128 1.01 (0.85–1.21) 0.886
 Malignancy 1030 (18.1%) 412 (27.4%) 0.58 (0.50–0.69) 0.000 0.71 (0.59–0.89) 0.000
 No reported illness 580 (23.0%) 198 (16.7%) 1.48 (1.24–1.77) 0.000 1.36 (1.10–1.68) 0.005
Diagnostic tests
 Bilateral disease on CXRc 414 (36.7%) 1094 (46.0%) 1.47 (1.27–1.70) 0.000 1.30 (1.11–1.52) 0.001
 AFB smear test (+) 1254 (50.6%) 499 (42.9%) 1.36 (1.18–1.56) 0.000 1.30 (1.11–1.52) 0.001
Symptoms
 Dyspnea 924 (36.3%) 326 (27.4%) 1.51 (1.30–1.76) 0.000 1.52 (1.29–1.79) 0.000
 Fever 369 (14.5%) 140 (11.8%) 1.27 (1.03–1.57) 0.023 1.21 (0.96–1.55) 0.104
  1. OR, odds ratio; aOR, adjusted odds ratio; CI, confidence interval; CXR, chest X-ray; AFB, acid-fast bacillus
  2. % = % of cases without missing data
  3. aAll the variables listed in this table were used in the multivariate analysis
  4. b Never smoker was used as reference
  5. c Unilateral disease on chest X-ray was used as reference