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Table 2 Antiretroviral therapy data of patients in cohort

From: Incidence of tuberculosis among HIV infected individuals on long term antiretroviral therapy in private healthcare sector in Pune, Western India

Characteristics

Total patients (n = 1904)

Prevalent TB at baseline

p-value

No

Yes

Total patients, n (%)

1904 (100%)

1267 (66.5%)

637 (33.5%)

 

ART regimes (n = 1894)b, n (%)

0.947

 NNRTI based

1482 (78.2%)

983 (66.3%)

499 (33.7%)

 

 PI based

413 (21.8%)

275 (66.5%)

138 (33.5%)

 

Duration since HIV diagnosis (Months), Median (IQR) a

62 (36.0, 92.0)

61 (34.0, 92.0)

64 (36.0, 94.0)

0.231

Duration on ART (Months), Median (IQR)a

57 (32.0, 84.0)

56 (32.0, 85.0)

60 (32.0, 82.0)

0.382

CD4 count at ART initiation, Median (IQR) a

173 (83.0, 255.0)

197 (112.0, 297.0)

108 (58.0, 182.0)

< 0.0001

CD4 count NADIR, Median (IQR) a

146 (72.0, 235.0)

183 (88.0, 277.0)

88 (49.0, 165.0)

< 0.0001

Current/updated CD4 count, Median (IQR) a

402 (236, 620)

440 (286, 664)

331 (187, 521)

< 0.0001

Virologic condition on ART, n (%)

< 0.0001

 Virologic failure (VF)

297 (15.6%)

166 (55.9%)

131 (44.1%)

 

 Virologic suppression (VS)

1607 (84.4%)

1101 (68.5%)

506 (31.5%)

 

IPT on ART, n (%)

0.001

 ART plus IPT given

358 (18.8%)

264 (73.7%)

94 (26.3%)

 

 ART alone

1546 (81.2%)

1003 (64.9%)

543 (35.1%)

 
  1. ART antiretroviral therapy, IPT ionized preventive therapy, IQR interquartile range, NNRTI nonnucleoside reverse transcriptase inhibitor, PI protease inhibitor, TB tuberculosis. a Median test, bIntegrase inhibitor based ART regimen was given to 10 patients