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Table 1 Performance of rK39 ICTs on Human and Canine samples from endemic areas in Colombia

From: Evaluation of four rapid diagnostic tests for canine and human visceral Leishmaniasis in Colombia

Parameter evaluated

Human

Canine

Kalazar Detect™

ad-bio Leishmania IgG/IgM

Combo Rapid Test

Kalazar Detect™ Rapid Test, Canine

DPP® CVL rapid test

Value

CI 95%

Value

CI 95%

Value

CI 95%

Value

CI 95%

Sensitivity

91.5%

(83.4–95.8)

91.5%

(83.4–95.8)

82.9%

(72.38–89.91)

85.7%

(75.66–92.05)

Specificity

89.2%

(80.1–94.4)

93.2%

(85.1–97.1)

92.6%

(82.45–97.08)

79.6%

(67.1–88.23)

PPV

90.4%

(82.1–95.0)

93.8%

(86.19–97.3)

93.6%

(84.55–97.46)

84.5%

(74.35–91.12)

NPV

90.4%

(81.5–95.3)

90.8%

(82.2–95.5)

80.6%

(69.15–88.57)

81.1%

(68.64–89.41)

LR (+)

8.46

(6.61–10.84)

13.54

(9.12–20.08)

11.19

(6.80–18.39)

4.21

(3.502–5.056)

LR (−)

0.096

(0.072–0.127)

0.092

(0.069–0.121)

0.185

(0.157–0.219)

0.179

(0.146–0.221)

  1. PPV Positive Predictive Value, NPV Negative Predictive Value, LR Likelihood Ratio