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Table 4 Comparison of Morbidity and Mortality by VRE infection

From: VRE in cirrhotic patients

Outcomea VRE Positive VRE Negative, Gram Negative p-value VRE Positive VRE Negative, Sterile p-value
1-year mortalityb
 Mortality, n (%) 22 (48.9%) 18 (30.5%)   22 (48.9%) 44 (26.7%)  
 Unadjusted OR (95% CI) 2.18 (0.97, 4.88)   0.06 2.63 (1.33, 5.19)   0.005
 OR (95% CI) adjusted for:       
  Age, Hispanic, Sex 2.96 (1.23, 7.14)   0.02 2.87 (1.39, 5.93)   0.005
  Age, Hispanic, Sex, Child Pugh 2.06 (0.81, 5.27)   0.13 2.04 (0.95, 4.38)   0.07
  Age, Hispanic, Sex, Meld 2.26 (0.88, 5.84)   0.09 1.97 (0.88, 4.41)   0.10
30-day mortalityc
 Mortality, n (%) 10 (17.9%) 10 (13.5%)   10 (17.9%) 36 (14.9%)  
 Unadjusted OR (95% CI) 1.39 (0.54, 3.62)   0.50 1.24 (0.57, 2.67)   0.59
 OR (95% CI) adjusted for
  Age, Hispanic, Sex 1.66 (0.61, 4.50)   0.32 1.27 (0.57, 2.85)   0.56
  Age, Hispanic, Sex, Child Pugh 1.10 (0.39, 3.15)   0.86 0.74 (0.32, 1.72)   0.49
  Age, Hispanic, Sex, Meld 1.09 (0.36, 3.30)   0.88 0.58 (0.23, 1.46)   0.25
Hospital length of stay (days)
 Unadjusted mean days (95% CI) 24.8 (18.4, 31.3) 10.7 (8.1, 13.3) < 0.001 25.4 (19.6, 31.2) 7.7 (6.8, 8.6) < 0.001
 Mean days (95% CI) adjusted for
  Age, Hispanic, Sex 25.3 (18.4, 32.3) 10.6 (7.9, 13.2) < 0.001 24.3 (18.6, 30.0) 7.8 (6.9, 8.7) < 0.001
  Age, Hispanic, Sex, Child Pugh 25.1 (18.4, 31.8) 10.7 (8.1, 13.4) < 0.001 23.8 (18.3, 29.3) 7.9 (7.0, 8.8) < 0.001
  Age, Hispanic, Sex, Meld 24.7 (18.2, 31.2) 11.2 (8.3, 14.0) < 0.001 21.9 (17.0, 26.8) 8.2 (7.2, 9.2) < 0.001
ICU length of stay (days)
 Unadjusted mean days (95% CI) 12.9 (6.0, 19.8) 3.3 (1.7, 4.9) < 0.001 12.9 (5.9, 19.9) 2.5 (1.8, 3.1) < 0.001
 Mean days (95% CI) adjusted for
  Age, Hispanic, Sex 14.3 (6.0, 22.5) 3.1 (1.6, 4.6) < 0.001 12.6 (5.7, 19.6) 2.5 (1.3, 3.1) < 0.001
  Age, Hispanic, Sex, Child Pugh 15.8 (6.4, 25.1) 3.0 (1.5, 4.5) < 0.001 12.3 (5.5, 19.1) 2.6 (1.9, 3.3) < 0.001
  Age, Hispanic, Sex, Meld 14.0 (5.5, 22.6) 3.1 (1.4, 4.8) < 0.001 10.4 (4.8, 15.9) 2.7 (1.8, 3.5) < 0.001
  1. a1-year and 30-day mortality compared by logistic regression; hospital length of stay compared by zero-truncated negative binomial regression; ICU length of study compared by negative binomial regression. Meld covariate 3-level (≤20, 21–30, ≥31).
  2. b1-year mortality evaluated among 104 (45 VRE-positive, 59 VRE- gram negative) subjects with minimum of 1-year follow-up. 1-year mortality evaluated among 210 (45 VRE-positive, 165 VRE-negative, sterile) subjects with minimum of 1-year follow-up.
  3. c30-day mortality evaluated among 130 (56 VRE-positive, 74 VRE- gram negative) subjects with minimum of 30-day follow-up. 30-day mortality evaluated among 297 (56 VRE-positive, 241 VRE-negative, sterile) subjects with minimum of 30-day follow-up.