Variable | Cases (n = 8) | Control (n = 23) | p-value |
---|---|---|---|
Initial antimicrobial regimen duration (days) | 3.5 ± 4.7 | 4.3 ± 3.4 | 0.52 |
Final antimicrobial regimen duration (days) | 8.6 ± 3.7 | 12.8 ± 4.6 | 0.03 |
Total antimicrobial treatment duration (days) | 9.5 ± 3.7 | 15.2 ± 3.7 | 0.007 |
Narrow spectrum antibiotic treatment duration (% from total duration) | 78 ± 11 | 40 ± 9 | 0.03 |
Duration of guideline-adherent antimicrobial regimen (% from total duration) | 93 ± 3 | 45 ± 9 | 0.006 |
Administration of steroids | 3 (38) | 9 (39) | 0.94 |
Antimicrobial chemoprophylaxis for close contacts | 4 (50) | 1 (4) | 0.01 |
In-hospital mortality | 2 (25) | 1 (4) | 0.31 |
ICU admission duration (%) | 21 ± 35 | 14 ± 26 | 0.5566 |
ICU admission | 4 (50) | 9 (39) | 0.9 |
Length of stay (days) | 10 ± 4 | 17 ± 9 | 0.065 |
Poor functional outcome (mRS ≥ 4) | 2 (25) | 3 (13) | 0.82 |