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Table 2 Comparison of primary and secondary outcome measures in TASMC groups

From: Clinical benefits of FilmArray meningitis-encephalitis PCR assay in partially-treated bacterial meningitis in Israel

Variable

Cases (n = 8)

Control (n = 23)

p-value

Initial antimicrobial regimen duration (days)

3.5 ± 4.7

4.3 ± 3.4

0.52

Final antimicrobial regimen duration (days)

8.6 ± 3.7

12.8 ± 4.6

0.03

Total antimicrobial treatment duration (days)

9.5 ± 3.7

15.2 ± 3.7

0.007

Narrow spectrum antibiotic treatment duration (% from total duration)

78 ± 11

40 ± 9

0.03

Duration of guideline-adherent antimicrobial regimen (% from total duration)

93 ± 3

45 ± 9

0.006

Administration of steroids

3 (38)

9 (39)

0.94

Antimicrobial chemoprophylaxis for close contacts

4 (50)

1 (4)

0.01

In-hospital mortality

2 (25)

1 (4)

0.31

ICU admission duration (%)

21 ± 35

14 ± 26

0.5566

ICU admission

4 (50)

9 (39)

0.9

Length of stay (days)

10 ± 4

17 ± 9

0.065

Poor functional outcome (mRS ≥ 4)

2 (25)

3 (13)

0.82

  1. Bold values are significant