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Table 2 Association of prior exposure to TA and/or ddI with low VAT and SAT density

From: Long-lasting alterations in adipose tissue density and adiponectin production in people living with HIV after thymidine analogues exposure

  Low visceral adipose tissue density Low subcutaneous adipose tissue density
Crude OR [95% CI] Adjusted OR [95% CI]* Crude OR [95% CI] Adjusted OR [95% CI]**
Prior exposure to TA and/or ddI 2.76 [1.97; 3.87] 1.74 [1.14; 2.67] 1.61 [1.17; 2.22] 1.74 [1.18; 2.58]
Age, per 10 years 1.78 [1.53; 2.07] 1.23 [1.01; 1.50] 1.23 [1.07;1.42] 1.17 [0.98; 1.40]
Sex, male 2.21 [1.25; 3.90] 1.73 [0.84; 3.57] 0.84 [0.53; 1.31] 2.90 [1.57; 5.35]
VAT area, per 50cm2 increase 2.18 [1.91; 2.49] 1.89 [1.59; 2.25]
SAT area, per 50cm2 increase 1.28 [1.16; 1.42] 2.00 [1.64; 2.43]
  1. Abbreviations: visceral adipose tissue, VAT; subcutaneous adipose tissue, SAT; thymidine nucleoside analog reverse-transcriptase inhibitors, TA; didanosine, ddI. Multivariable models were adjusted for: age, sex, origin, physical activity, BMI, smoking, VAT* (or SAT**) area, and prior exposure to TA and/or ddI