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Table 3 Factors associated with MTB strains harboring inhA mutation in 2015

From: Change in prevalence and molecular characteristics of isoniazid-resistant tuberculosis over a 10-year period in China

Characteristics No. of INH-resistant isolates (%) P value OR (95% CI)
With inhA mutation
(n = 28)
Without inhA mutation
(n = 77)
Sex
 Men 18(64.3) 51(66.2) 0.85 1.09(0.44–2.70)
 Women 10(35.7) 26(33.8)   1.00(Ref)
Age group (years)
 <25 3(10.7) 6(7.8) 0.39 0.47(0.10–2.30)
 25–44 8(28.6) 34(44.2)   1.00(Ref)
 45–64 12(42.9) 27(35.1) 0.22 0.53(0.19–1.48)
 >64 5(17.9) 10(13.0) 0.29 0.47(0.13–1.76)
Treatment History
 New case 16(35.7) 47(79.2)   1.00(Ref)
 Re-treated 12(64.3) 30(20.8) 0.72 0.85(0.35–2.05)
Previous drug exposure
 INH 12(77.8) 30(26.0) 0.72 0.85(0.35–2.05)
 RIF 12(77.8) 30(26.0) 0.72 0.85(0.35–2.05)
 EMB 12(77.8) 30(26.0) 0.72 0.85(0.35–2.05)
 PZA 12(77.8) 30(26.0) 0.72 0.85(0.35–2.05)
 SLID 8(32.1) 19(15.6) 0.69 0.82(0.31–2.16)
 FQ 10(39.3) 22(20.8) 0.48 0.72(0.29–1.80)
 PTH 6(21.4) 4(5.2) 0.02 0.20(0.05–0.78)