Table 1 Characteristics of the 8 normal controls and 10 sepsis patients used for whole-exome sequencing
Variables | Normal controls (n = 8) | Sepsis patients (n = 10) | P value | ||
|---|---|---|---|---|---|
Survivors (n = 5) | Non-survivors (n = 5) | P′ value | |||
Age (years) | 66 (35, 78) | 67 (34, 77) | 73 (49, 74) | 0.917 | 0.790 |
Sex (Female/Male) | 4/4 | 2/3 | 3/2 | 0.738 | 0.681 |
Cause of sepsis (n) | |||||
Lung infection | – | 2 | 2 | – | – |
Post-operative | – | 1 | 0 | – | – |
Multiple trauma | – | 1 | 2 | – | – |
Others | – | 1 | 1 | – | – |
SOFA score | – | 6 (0,7) | 8 (5,18) | 0.151 | – |
APACHE II | – | 10 (5, 14) | 13 (5,23) | 0.548 | – |
CRP (mg/dl) | – | 7.2 (1.3, 11.73) | 9.23 (2.13, 16.78) | 0.548 | – |
PCT (ng/ml) | – | 5.92 (0.05, 9.34) | 4.68 (0.1, 64.43) | 0.690 | – |
WBC(×109/l) | – | 8.25 (3.01, 35.82) | 12.68 (8.8, 17.14) | 0.690 | – |