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Table 1 Summary of investigations divided by date and location of collection. Appropriate anti-fungal therapy was started on day 27 of symptoms

From: A case report of Coccidioides posadasii meningoencephalitis in an immunocompetent host

Sample

Test

Result

Blood

 Day 22

Antibodies against arbovirus antigens.

Negative

 Day 28

Bartonella henselae IgG

Negative

Blastomyces Immunodiffusion IgG

Negative

Coccidioidal IgG

Positive

Coccidioidal IgM

Negative

Coccidiodal Immunodiffusion IgG

Negative

HIV 1 and HIV 2 antibody

Negative

Toxoplasma IgG and IgM

Negative

Syphilis antibody

Negative

 Day 29

Mycobacterial culture

Negative

 Day 30

Flow cytometry for lymphoma

Negative

Coccidiodal PCR

Positive

(pan-fungus primers targeting ribosomal RNA genes and ITS sequences)

(Coccidiodes posadasii)

Cerebrospinal fluid

 Day 22

Antibodies against arbovirus antigens

Negative

Enterovirus RT-PCR

Negative

Herpes simplex virus PCR

Negative

Varicella zoster virus PCR

Negative

West Nile virus RT-PCR

Negative

Mycobacteria (AFB) GeneXpert

Negative

 Day 30

Cryptococcal antigen

Negative

Mycobacteria (AFB) smear and culture

Negative

Coccidioidal IgG

Positive

Coccidioidal IgM

Positive

Coccidiodal Immunodiffusion IgG

Negative

Stool

 Day 30

Mycobacteria (AFB) Smear and Culture

Negative