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Table 3 Effectiveness (95% CI) of pneumococcal conjugate vaccine according to the case-control studies by HIV infection status and vaccine valency

From: Effectiveness of pneumococcal conjugate vaccination against invasive pneumococcal disease among children with and those without HIV infection: a systematic review and meta-analysis

HIV status PCVa PCV7 PCV13 Overall
HI 10.4(−100.1, 60.0) 7.8(−68.2, 49.5) −251(− 1944, 40.0) −6.2% (− 67.6, 32.7)
HUI 80.7 (47.3, 90.1) 60.5 (30.0, 77.7) b 57.8 (0.5, 82.1) 65.1% (47.3, 76.9)
  1. HI HIV-infected, HUI HIV-uninfected, PCV pneumococcal conjugate vaccine
  2. a Unspecified vaccine valency in primary studies
  3. b Meta-analysis was done despite of moderate heterogeneity (I-squared around 50%); more details in Additional file 1