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Table 1 Characteristics of 36,498 eligible females 15–45 years of age with known pregnancy status

From: Pregnancy as a risk factor for severe influenza infection: an individual participant data meta-analysis

Author Eligible females (n) Pregnant (%) Mortality (%) Hospital admission(%) ICU admission(%) Country of origin Study Levelc
CDC/FluSurv-NETb [7,8,9] 2531 27.1 2.1 N/A 17.5 USA Hospital
CNISPb [10] 529 24.4 3.0 N/A 20.6 Canada Hospital
D’Ortenziob [11] 17 35.3 47.1 N/A N/A Réunion Island ICU
Echevarria-Zuno [12, 13] 25,206 6.0 1.1 9.9 11.8a Mexico Community
Fuhrmannb [14] 528 38.4 9.8a N/A 24.2a France Hospital/ICU
Harrisb [15] 51 54.9 2.0a 39.2 15.6a Australia Community
Helferty [16] 889 29.9 7.5a N/A 19.2 Canada Hospital
Huang [17] 141 7.1 5.7 N/A 24.1 Taiwan Hospital
Jain [18] 67 26.9 6 N/A 24.2 USA Hospital
Joves Sevic [19] 14 21.4 21.4 N/A N/A Serbia ICU
Kelly [20] 317 23.3 4.7 N/A 29.3 Australia Hospital
Kusznierz [21] 48 29.2 39.6 N/A 52.1 Argentina Hospital
Lehnersb [22] 56 51.8 0.0 55.4 10.7 Germany Community
Lenzid [23] 488 29.5 15 52.7 N/A Brazil Community
Limb [24] 197 41.1 1.5 N/A 5.6 Singapore Hospital
Malonda [25] 274 46.4 4.2a 86.9 11.1 Spain Community
Martin-Loechesb [26] 452 20.6 13.9 N/A N/A Spain ICU
Mehta [27] 36 16.7 13.9 N/A N/A India Hospital
Mulrennan [28] 22 22.7 0.0 N/A 22.7 Australia Hospital
Nishiokab 1557 25.8 11.1 N/A 24.6 Brazil Hospital
Oh [29] 176 11.9 0.6 N/A 4 South Korea Hospital
Orellano [30] 1689 7.1 2.7 60.5 N/A Argentina Community
Poeppl [31] 42 35.7 9.5 69 9.5 Austria Community
Riquelmeb [32] 73 52.1 8.3 72.6 16.4 Spain, Chile Community
Riquelmeb [33] 99 16.2 15.2 N/A 34.7 Global Hospital
Sertogullarindan [34] 9 22.2 22.2 N/A N/A Turkey ICU
Skarbinski [35] 68 42.6 7.7 N/A 25 USA Hospital
Thompson [36] 141 35.5 4.3 N/A 21.3 USA Hospital
Van’t Klooster [38] 339 19.5 0.9 N/A 9.7 Netherlands Hospital
Viasus [39] 210 46.7 2.4 N/A 10.5 Spain Hospital
Xu [40] 103 54.4 20.4 N/A 38.6 China Hospital
Yangb [41] 114 14.9 11.4 93 21.2 China Community
Zolotusca [42] 15 20.0 13.3 N/A 53.3 Romania Hospital
  1. aNote percentages in Table 1 were based on valid data only; missing data were not included in the calculation
  2. bAdditional data that was not included in the original publication was provided, unpublished data (Nishioka), and/or several publications based on the dataset provided (CDC, CNISP). FluSurv-NET = Influenza Hospitalization Surveillance Network
  3. cStudies were considered conducted in a ‘community’ setting if participants were seeking health care but have not yet been admitted to a hospital
  4. dOnly a partial dataset available
  5. N/A either no data available or not applicable, e.g. hospital admission as an outcome in a population that was hospitalized as an inclusion criterion for the study. ICU: intensive care unit