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Table 1 Characteristics of 36,498 eligible females 15–45 years of age with known pregnancy status

From: Pregnancy as a risk factor for severe influenza infection: an individual participant data meta-analysis

Author

Eligible females (n)

Pregnant (%)

Mortality (%)

Hospital admission(%)

ICU admission(%)

Country of origin

Study Levelc

CDC/FluSurv-NETb [7,8,9]

2531

27.1

2.1

N/A

17.5

USA

Hospital

CNISPb [10]

529

24.4

3.0

N/A

20.6

Canada

Hospital

D’Ortenziob [11]

17

35.3

47.1

N/A

N/A

Réunion Island

ICU

Echevarria-Zuno [12, 13]

25,206

6.0

1.1

9.9

11.8a

Mexico

Community

Fuhrmannb [14]

528

38.4

9.8a

N/A

24.2a

France

Hospital/ICU

Harrisb [15]

51

54.9

2.0a

39.2

15.6a

Australia

Community

Helferty [16]

889

29.9

7.5a

N/A

19.2

Canada

Hospital

Huang [17]

141

7.1

5.7

N/A

24.1

Taiwan

Hospital

Jain [18]

67

26.9

6

N/A

24.2

USA

Hospital

Joves Sevic [19]

14

21.4

21.4

N/A

N/A

Serbia

ICU

Kelly [20]

317

23.3

4.7

N/A

29.3

Australia

Hospital

Kusznierz [21]

48

29.2

39.6

N/A

52.1

Argentina

Hospital

Lehnersb [22]

56

51.8

0.0

55.4

10.7

Germany

Community

Lenzid [23]

488

29.5

15

52.7

N/A

Brazil

Community

Limb [24]

197

41.1

1.5

N/A

5.6

Singapore

Hospital

Malonda [25]

274

46.4

4.2a

86.9

11.1

Spain

Community

Martin-Loechesb [26]

452

20.6

13.9

N/A

N/A

Spain

ICU

Mehta [27]

36

16.7

13.9

N/A

N/A

India

Hospital

Mulrennan [28]

22

22.7

0.0

N/A

22.7

Australia

Hospital

Nishiokab

1557

25.8

11.1

N/A

24.6

Brazil

Hospital

Oh [29]

176

11.9

0.6

N/A

4

South Korea

Hospital

Orellano [30]

1689

7.1

2.7

60.5

N/A

Argentina

Community

Poeppl [31]

42

35.7

9.5

69

9.5

Austria

Community

Riquelmeb [32]

73

52.1

8.3

72.6

16.4

Spain, Chile

Community

Riquelmeb [33]

99

16.2

15.2

N/A

34.7

Global

Hospital

Sertogullarindan [34]

9

22.2

22.2

N/A

N/A

Turkey

ICU

Skarbinski [35]

68

42.6

7.7

N/A

25

USA

Hospital

Thompson [36]

141

35.5

4.3

N/A

21.3

USA

Hospital

Van’t Klooster [38]

339

19.5

0.9

N/A

9.7

Netherlands

Hospital

Viasus [39]

210

46.7

2.4

N/A

10.5

Spain

Hospital

Xu [40]

103

54.4

20.4

N/A

38.6

China

Hospital

Yangb [41]

114

14.9

11.4

93

21.2

China

Community

Zolotusca [42]

15

20.0

13.3

N/A

53.3

Romania

Hospital

  1. aNote percentages in Table 1 were based on valid data only; missing data were not included in the calculation
  2. bAdditional data that was not included in the original publication was provided, unpublished data (Nishioka), and/or several publications based on the dataset provided (CDC, CNISP). FluSurv-NET = Influenza Hospitalization Surveillance Network
  3. cStudies were considered conducted in a ‘community’ setting if participants were seeking health care but have not yet been admitted to a hospital
  4. dOnly a partial dataset available
  5. N/A either no data available or not applicable, e.g. hospital admission as an outcome in a population that was hospitalized as an inclusion criterion for the study. ICU: intensive care unit