| Variable | N | SFCs to ESAT-6 | SFCs to CFP-10 |
|---|
| SFCs/250000PBMCs | Test value | P value | SFCs/250000PBMCs | Test value | P value |
|---|
| Total | 360 | 69.0 (24.3–148.3) | | | 83.5 (23.0–218.3) | | |
| Sex |
| Female | 79 | 87.0 (42.0–155.0) | | | 97.0 (42.0–200.0) | | |
| Male | 281 | 66.0 (22.5–134.5) | Z = 12,681.5 | 0.053 | 82.0 (21.0–227.0) | Z = 11,627.5 | 0.518 |
| Smokinga |
| No | 147 | 71.0 (37.0–143.0) | | | 92.0 (29.0–234.0) | | |
| Yes | 213 | 66.0 (20.0–150.0) | Z = 14,353.0 | 0.180 | 82.0 (21.5–205.5) | Z = 15,138.0 | 0.594 |
| Dust exposurea |
| No | 257 | 69.0 (27.0–146.5) | | | 82.0 (22.0–200.0) | | |
| Yes | 103 | 59.0 (19.0–150.0) | Z = 12,438.5 | 0.372 | 85.0 (28.0–237.0) | Z = 13,966.0 | 0.413 |
| Previously treated cases |
| Nob | 257 | 74.0 (28.5–150.0) | | | 91.0 (23.0–235.5) | | |
| Yesc | 103 | 54.0 (13.0–97.0) | Z = 10,233.0 | 0.001 | 65.0 (23.0–200.0) | Z = 12,289.5 | 0.289 |
| Cavitation |
| No | 137 | 72.0 (26.5–144.0) | | | 91.0 (18.0–200.0) | | |
| Yes | 223 | 67.0 (24.0–150.0) | Z = 15,093.0 | 0.849 | 82.0 (24.0–257.0) | Z = 15,772.5 | 0.604 |
| Extrapulmonary tuberculosis |
| No | 297 | 69.0 (24.0–150.0) | | | 82.0 (23.0–200.0) | | |
| Yes | 63 | 66.0 (25.0–114.0) | Z = 8997.5 | 0.633 | 121.0 (24.0–300.0) | Z = 9996.5 | 0.393 |
| Diabetes mellitus |
| No | 330 | 70.0 (24.8–150.0) | | | 87.0 (24.0–220.3) | | |
| Yes | 30 | 38.5 (22.0–89.5) | Z = 3920.0 | 0.059 | 49.5 (7.8–216.0) | Z = 4321.0 | 0.249 |
| Drug-resistant tuberculosis |
| No | 327 | 69.0 (25.0–150.0) | | | 85.0 (23.0–220.0) | | |
| Yes | 33 | 65.0 (15.5–134.5) | Z = 5181.0 | 0.707 | 71.0 (25.0–199.0) | Z = 5409.0 | 0.981 |
| Staged |
| Minimal/Mild | 2 | 77.5 (0.0–77.50) | | | 85.5 (22.0–85.5) | | |
| Moderate | 143 | 78.0 (38.0–150.0) | | | 97.0 (41.0–264.0) | | |
| Advanced | 215 | 64.0 (22.0–126.0) | SRCC = -0.095 | 0.071 | 82.0 (15.0–211.0) | SRCC = 0.000 | 0.995 |
| Gradee |
| DNA/RNA positive | 80 | 68.0 (27.3–99.5) | | | 84.0 (22.5–251.8) | | |
| The number of colony | 24 | 104.0 (51.8–203.5) | | | 132.5 (24.8–262.5) | | |
| 1+ | 102 | 67.0 (21.8–150.0) | | | 77.0 (22.8–205.0) | | |
| 2+ | 50 | 59.5 (25.5–142.3) | | | 81.0 (21.3–291.8) | | |
| 3+ | 70 | 69.0 (24.5–150.0) | | | 86.0 (26.8–200.0) | | |
| 4+ | 34 | 65.5 (30.3–126.8) | SRCC = -0.075 | 0.158 | 59.5 (19.3–154.8) | SRCC = -0.029 | 0.587 |
- Data are presented as N, median (interquartile range). There were no missing values
- a: Smoking or dust exposure for at least 3 months before a diagnosis of pulmonary tuberculosis
- b: New cases are defined as not starting anti-TB treatment or being on anti-TB treatment for <1 month
- c: Previously treated cases are defined as those anti-TB treated ≥1 month in the past
- d: The staging standard of National Tuberculosis Association of the United States of America
- e: Smear grading before treatment
- CFP-10 Culture filtrate protein 10 kDa, DNA Deoxyribonucleic acid, ESAT-6 Early secreted antigenic target 6 kDa, PBMCs Peripheral blood mononuclear cells, RNA Ribonucleic acid, SFCs Spot-forming cells, SRCC Spearman’s rho correlation coefficient, Z Wilcoxon’s rank sum test
