Citation | Age | Gender | Virus type | Manifestation | HRCT | Time to biopsy | Biopsy/autopsy | Pathology | Treatment | Outcome |
---|---|---|---|---|---|---|---|---|---|---|
Staud, 2001 [4] | 59 | F | A | Respiratory failure | Consolidation | NR | OLB | OP | Intravenous steroids and azathioprine | Survival |
Fujita, 2007 [6] | 38 | F | A | NR | Consolidation | NR | NR | OP | Steroid pulse therapy | Survival |
Fujita, 2014 [7] | 97 | F | A | Respiratory failure | Not examined | 12 days | Autopsy | OP, DAD, hemorrhage and bronchiolitis | NR | Dead |
24 | F | H1N1 | Respiratory failure | Consolidation and GGO | 16 days | Autopsy | OP and DAD | NR | Dead | |
37 | M | H1N1 | Respiratory failure | GGO | 15 days | Autopsy | OP, hemorrhage and edema | NR | Dead | |
Marchiori, 2011 [8] | 52 | M | H1N1 | NR | linear opacity | NR | NR | OP | NR | NR |
Torrego, 2010 [9] | 55 | F | H1N1 | Dyspnea and cough | Consolidation | Over 30 days | TBLB | OP with viral cytopathic changes | Prednisone, 0.75 mg/kg/d | C/R improvement |
Cornejo, 2010 [3] | 52 | F | H1N1 | Respiratory failure | Consolidation | Over 8 days | OLB | OP, bronchiolar necrosis and squamous metaplasia | Methylprednisolone, 500 mg/d for 3d | improvement |
36 | M | H1N1 | Fever, increased inflammatory parameters, and respiratory failure | Consolidation and loss of global lung volume | Over 3 weeks | OLB | OP, hemorrhage and edema | The same as above | C/R improvement | |
Gómez-Gómez, 2011 [10] | 44 | F | H1N1 | Cough, dyspnea and fever | Intralobular interstitial thickening and GGO | Over 3 weeks | TBLB | OP | Steroid, 1 mg/kg/day for 1 m 0.5 mg/kg/d for 6w | C/R improvement |
60 | M | H1N1 | Cough and dyspnea | Consolidation and GGO | Over 3 weeks | TBLB | OP | The same as above | C/R improvement | |
Kwok, 2016 [5] | 45 | F | B | Dyspnea | GGO and lung cyst | Over 28 days | TBLB | OP | Prednisolone, 30 mg/d with 2 m tapering | C/R improvement |
NR | F | A | NR | NR | NR | NR | NR | Steroid | Improvement with lung fibrosis and residual dyspnea | |
This case | 35 | M | H7N9 | Fever, respiratory failure | Consolidation and GGO | 39 days | OLB | OP, hemorrhage and edema | Methylprednisolone, 1.5 mg/kg/d for 5d, | C/R improvement |