Table 2 Comparison of demographics and clinical characteristics of hospitalized and non-hospitalized patients of HAdV infection between 2011 and 2014 epidemics

Age

5.0 ± 3.1

4.4 ± 3.5

5.1 ± 3.3

4.7 ± 3.5

0.045

0.209

Gender (M/F ratio)

1.08

1.57

1.33

1.63

0.072

0.297

Co-infection

7 (1.6)

8 (4.2)

6 (1.7)

16 (10.1)

0.081

< 0.001*

Underlying disease

29 (6.5)

28 (14.8)

8 (2.3)

23 (14.6)

0.001*

< 0.001*

 Acute pharyngitis/PCF

350 (78.5)

73 (38.6)

284 (80.7)

101 (63.9)

< 0.001

< 0.001

 Bronchiolitis/bronchopneumonia

60 (13.5)

74 (39.2)

55 (15.6)

58 (36.7)

< 0.001

< 0.001*

 Pneumonia

1 (0.2)

20 (10.6)

0 (0.0)

8 (5.1)

< 0.001

< 0.001

 Acute gastro-enterocolitis

34 (7.6)

26 (13.8)

16 (4.5)

14 (8.9)

0.016

0.055

 Fever

378 (84.8)

168 (88.9)

352 (100.0)

158 (100.0)

0.17

–

 Injected throat

406 (91.0)

157 (83.1)

344 (97.7)

152 (96.2)

0.004

0.381

 Cough

259 (58.1)

151 (79.9)

282 (80.1)

140 (88.6)

< 0.001*

0.019

 Rhinorrhea

229 (51.3)

112 (59.3)

271 (77.0)

132 (83.5)

0.067

0.093

 Conjunctivitis

35 (7.8)

16 (8.5)

46 (13.1)

23 (14.6)

0.793

0.649

 Abdominal pain

66 (14.8)

33 (17.5)

59 (16.8)

30 (19.0)

0.398

0.540

 Diarrhea

97 (21.7)

56 (29.6)

43 (12.2)

44 (27.8)

0.034

< 0.001*

 Vomiting

146 (32.7)

72 (38.1)

75 (21.3)

61 (38.6)

0.193

< 0.001*

 WBC (cells/μL)

5051 ± 6336

12,044 ± 5983

6000 ± 6683

13,130 ± 5825

< 0.001

< 0.001*

 ANC (cells/μL)

14,857 ± 77,292

8312 ± 5207

15,095 ± 101,895

9076 ± 4865

0.217

0.465

 ALC (cells/μL)

2138 ± 1500

2624 ± 2307

2456 ± 1608

2670 ± 2097

0.015

0.286

 CRP (mg/L)

47.6 ± 33.4

80.8 ± 71.5

52.4 ± 39.5

77.4 ± 63.3

< 0.001*

< 0.001*

Survival rates

445 (99.8)

188 (99.5)

352 (100.0)

158 (100.0)

–

–