Table 1 Comparison of demographics, clinical characteristics and genotypes of patients with HAdV infection between 2011 and 2014 epidemics
Variables | 2011 epidemics (N = 635) | 2014 epidemics (N = 510) | P-value |
|---|---|---|---|
Age (years) | 4.8 ± 3.3 | 4.9 ± 3.4 | 0.581 |
Gender (M/F ratio) | 1.19 | 1.42 | 0.145 |
Co-infection | 15 (2.4) | 22 (4.3) | 0.063 |
Underlying disease | 57 (9.0) | 31 (6.1) | 0.067 |
Diagnosis | |||
 Upper respiratory | |||
  Acute pharyngitis/ PCF | 423 (66.6) | 385 (75.5) | 0.001* |
 Lower respiratory | |||
  Bronchiolitis /bronchopneumonia | 134 (21.1) | 113 (22.2) | 0.666 |
  Pneumonia | 21 (3.3) | 8 (1.6) | 0.063 |
  Acute gastroenterocolitis | 60 (9.4) | 30 (5.9) | 0.026* |
Clinical Manifestation | |||
 Fever | 546 (86.0) | 510 (100.0) | < 0.001* |
 Infected throat | 563 (88.7) | 496 (97.3) | < 0.001* |
 Cough | 410 (64.6) | 422 (82.7) | < 0.001* |
 Rhinorrhea | 341 (53.7) | 403 (79.0) | < 0.001* |
 Conjunctivitis | 51 (8.0) | 69 (13.5) | 0.003* |
 Abdominal pain | 99 (15.6) | 89 (17.5) | 0.398 |
 Diarrhea | 153 (24.1) | 87 (17.1) | 0.004* |
 Vomiting | 218 (34.3) | 136 (26.7) | 0.005* |
Survival rates | 633 (99.7) | 510 (100.0) | 0.506 |
Genotype (total number) | n = 156 | n = 157 |  |
 Type1 | 8 (5.1) | 44 (28.0) | < 0.001* |
 Type2 | 18 (11.5) | 1 (0.6) | < 0.001* |
 Type3 | 101 (64.7) | 40 (25.5) | < 0.001* |
 Type4 | 0 (0) | 25 (15.9) | < 0.001* |
 Type5 | 2 (1.3) | 0 (0) | 0.248 |
 Type6 | 1 (0.6) | 14 (8.9) | < 0.001* |
 Type7 | 26 (16.7) | 33 (21.0) | 0.325 |