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Table 1 Comparison of demographics, clinical characteristics and genotypes of patients with HAdV infection between 2011 and 2014 epidemics

From: Comparative study of clinical and epidemiological characteristics of major pediatric adenovirus epidemics in southern Taiwan

Variables 2011 epidemics
(N = 635)
2014 epidemics
(N = 510)
P-value
Age (years) 4.8 ± 3.3 4.9 ± 3.4 0.581
Gender (M/F ratio) 1.19 1.42 0.145
Co-infection 15 (2.4) 22 (4.3) 0.063
Underlying disease 57 (9.0) 31 (6.1) 0.067
Diagnosis
 Upper respiratory
  Acute pharyngitis/ PCF 423 (66.6) 385 (75.5) 0.001*
 Lower respiratory
  Bronchiolitis /bronchopneumonia 134 (21.1) 113 (22.2) 0.666
  Pneumonia 21 (3.3) 8 (1.6) 0.063
  Acute gastroenterocolitis 60 (9.4) 30 (5.9) 0.026*
Clinical Manifestation
 Fever 546 (86.0) 510 (100.0) < 0.001*
 Infected throat 563 (88.7) 496 (97.3) < 0.001*
 Cough 410 (64.6) 422 (82.7) < 0.001*
 Rhinorrhea 341 (53.7) 403 (79.0) < 0.001*
 Conjunctivitis 51 (8.0) 69 (13.5) 0.003*
 Abdominal pain 99 (15.6) 89 (17.5) 0.398
 Diarrhea 153 (24.1) 87 (17.1) 0.004*
 Vomiting 218 (34.3) 136 (26.7) 0.005*
Survival rates 633 (99.7) 510 (100.0) 0.506
Genotype (total number) n = 156 n = 157  
 Type1 8 (5.1) 44 (28.0) < 0.001*
 Type2 18 (11.5) 1 (0.6) < 0.001*
 Type3 101 (64.7) 40 (25.5) < 0.001*
 Type4 0 (0) 25 (15.9) < 0.001*
 Type5 2 (1.3) 0 (0) 0.248
 Type6 1 (0.6) 14 (8.9) < 0.001*
 Type7 26 (16.7) 33 (21.0) 0.325
  1. Note: M/F ratio, male to female ratio; PCF, pharyngoconjunctival fever
  2. * P < 0.05