Table 2 Performance of potential diagnostic cut-offs
Assay (Unit) | Diagnostic cut-off | Sensitivity | Specificity | Youden’s J statistic |
|---|---|---|---|---|
IgG (AU/mL) | 70.3 | 81.0% | 83.1% | 0.641 |
82.7 | 78.6% | 91.2% | 0.698 | |
89.3 | 78.6% | 94.4% | 0.729 | |
91.8 | 76.2% | 94.4% | 0.706 | |
118.6 | 71.4% | 96.9% | 0.683 | |
IgA (U/mL) | 6.1 | 71.4% | 78.1% | 0.496 |
7.2 | 69.0% | 82.5% | 0.515 | |
8.2 | 64.3% | 89.4% | 0.537 | |
9.8 | 57.1% | 93.7% | 0.509 | |
10.7 | 52.4 | 95.0% | 0.474 | |
IgM (AU/mL) | 53.3 | 61.9% | 38.7% | 0.007 |
66.5 | 52.4% | 48.1% | 0.005 | |
73.3 | 50.0% | 53.7% | 0.038 | |
81.9 | 45.2% | 57.5% | 0.027 | |
84.0 | 42.9% | 59.4% | 0.022 | |
GM (ug/L) | 0.40 | 76.2% | 45.6% | 0.218 |
0.45 | 73.8% | 51.2% | 0.251 | |
0.50 | 71.4% | 58.1% | 0.296 | |
0.60 | 45.2% | 65.0% | 0.102 | |
0.70 | 33.3% | 73.1% | 0.065 |