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Table 3 Relationship between mutations in the QRDR region and the MICs for 23 C. striatum isolates and ATCC 6940

From: Bloodstream and catheter-related infections due to different clones of multidrug-resistant and biofilm producer Corynebacterium striatum

Number of isolates

Ciprofloxacin

GyrA (amino acids)

MIC (mg/L)

Phenotype

Position 87

Position 91

15

> 32

R

Val

Asp

2

> 32

R

Val

Asn

1

> 32

R

Phe

Asp

3

> 32

R

Phe

Ala

1

2

R

Tyr

Asp

1

0.125

S

Ser

Asp

ATCC 6940a

0.094

S

Ser

Asp

  1. a GenBank accession number AY559038