Skip to main content

Table 3 Predictive values of Pj PCR and betaglucan in serum at a pre-test probability of 20%

From: Serum-based diagnosis of Pneumocystis pneumonia by detection of Pneumocystis jirovecii DNA and 1,3-β-D-glucan in HIV-infected patients: a retrospective case control study

Index tests in serum Positive predictive value Negative predictive value
Pj PCR positive 0.46 1.0
Pj PCR with Ct ≤34a 0.71 0.99
BG ≥80 pg/mlb 0.45 0.99
BG ≥200 pg/mlb 0.63 0.98
BG ≥400 pg/mlb 0.69 0.97
Pj PCR positive and BG ≥200 pg/mlb 0.70 0.98
  1. Pj Pneumocystis jirovecii, PCP Pneumocystis jirovecii pneumonia, BG 1,3-ß-D-glucan
  2. The results are based on 26 patients with PCP and 21 HIV-infected negative controls
  3. aThree PCP patients whose serum samples had been analysed after 1:2 dilution were excluded
  4. bOne PCP patient whose serum sample was not analyzed for BG due to insufficient volume of serum was excluded
Back to article page

BMC Infectious Diseases

ISSN: 1471-2334

Contact us