|
Index tests in serum
|
Sensitivity (%) (95% CI)
|
Specificity (%) (95% CI)
|
|---|
|
Patients with PCP
|
HIV-infected control patients
|
Blood donors
|
|---|
|
n = 26
|
n = 21
|
n = 18
|
|---|
|
Pj PCR positive
|
100 (87–100)
|
71 (50–86)
|
100 (87–100)
|
|
Pj PCR with Ct ≤34a
|
96 (79–100)
|
90 (71–98)
|
100 (82–100)
|
|
BG ≥80 pg/mlb
|
96 (80–100)
|
71 (50–86)
|
100 (82–100)
|
|
BG ≥200 pg/mlb
|
92 (75–99)
|
86 (65–95)
|
100 (82–100)
|
|
BG ≥400 pg/mlb
|
88 (70–96)
|
90 (71–98)
|
100 (82–100)
|
|
Pj PCR positive and BG ≥200 pg/mlb
|
92 (75–99)
|
90 (71–98)
|
100 (82–100)
|
- Pj Pneumocystis jirovecii, PCP Pneumocystis jirovecii pneumonia, CI confidence interval, BG 1,3-ß-D-glucan
- aThree PCP patients whose serum samples had been analysed after 1:2 dilution were excluded
- bOne PCP patient whose serum sample was not analyzed for BG due to insufficient volume of serum was excluded
