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Table 4 Comparison of main diagnostic categories among FUO case-series in 2005–2015 and FUO case-series in 1995–2004

From: Fever of unknown origin (FUO): which are the factors influencing the final diagnosis? A 2005–2015 systematic review

  Old case-series (1995–2004) New case-series (2006–2014) p-value
N° of patients 1488 3164
Male (%) 56,2 49,6
Mean age 40,6 45,8
Infectious Diseases 545 (37%) 1197 (38%) 0,428
Neoplasm 167 (11%) 366 (12%) 0,731
NIID 236 (16%) 661 (21%) < 0,001
Others 155 (10%) 206 (7%) < 0,001
No diagnosis 385 (26%) 734 (23%) 0,051
  1. Variables with significant statistical association (p < 0,05) are in bold