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Table 3 10 most frequent diagnosis for infectious diseases, neoplasm and NIID in 18 case-series 2006–2014

From: Fever of unknown origin (FUO): which are the factors influencing the final diagnosis? A 2005–2015 systematic review

Diagnosis N° (%) N° of case-series including the diagnosis
Infectious Diseases (out of 1197 cases from 18 case-series where details are available)
 Mycobacterial diseases 440 (36.8%) 17
 Endocarditis 119 (9.9%) 15
 Brucellosis 58 (4.8%) 9
 Internal abscesses 49 (4.1%) 11
 Salmonellosis 43 (3.6%) 9
 CMV infections 43 (3.6%) 7
 Urinary tract infections 40 (3.3%) 11
 Sepsis 20 (1.7%) 4
 HIV/AIDS 20 (1.7%) 4
 Osteoarticular infections 18 (1.5%) 5
Neoplasms (out of 289 cases from 15 case-series where details are available)
 Lynphomas (including Hodgkin, Non-Hodgkin, not specified) 169 (58.5%) 9
 Solid tumors (not specified) 25 (8.7%) 4
 Leukemias 17 (5.9%) 7
 Other cancers (not specified) 14 (4.8%) 5
 Myelodysplastic syndrome 11 (3.8%) 7
 Colon cancers 10 (3.5%) 5
 Multiple mieloma 8 (2.8%) 6
 Gastric cancers 5 (1.7%) 3
 Mesotheliomas 5 (1.7%) 3
 Castleman’s diseases 4 (1.4%) 3
NIIDs (out of 642 cases from 17 case-series where details are available)
 Adult-onset Still’s disease 177 (27. 6%) 15
 Systemic Lupus Erythematosus 71 (11.1%) 14
 Vasculitis 63 (9.8%) 8
 Rheumatic Polymyalgia 44 (6.9%) 8
 Giant Cells Arteritis 32 (5.0%) 6
 Mixed connective diseases (not specified) 31 (4.8%) 5
 Sarcoidosis 21 (3.3% 7
 Rheumatoid Arthritis 17 (2.6%) 6
 Wegener Granulomatosis 14 (2.2%) 4
 Polyarteritis nodosa 13 (2.0%) 5