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Table 4 Meta-regression analysis to determine sources of heterogeneity

From: Diagnostic accuracy of in-house real-time PCR assay for Mycobacterium tuberculosis: a systematic review and meta-analysis

Intercept

Coefficient

P value

Relative diagnostic odds ratio (RDOR)

95% confidence interval

Intercept

5.347

0.0000

–

–

Threshold (S)

0.169

0.5382

–

–

TB high-burden country vs. other country

0.756

0.3056

2.13

(0.46;9.96)

IS6110 vs. other target sequences

−0.812

0.2266

0.44

(0.11;1.77)

Cross-sectional design vs. case-control design

−0.759

0.5102

0.47

(0.04;5.45)

High-quality level vs moderate/low-quality level

1.175

0.0272

3.24

(1.17;9.00)

Respiratory specimens vs non-respiratory specimens /both

2.262

0.0025

9.60

(2.54;36.25)

  1. High-quality study: a study that had no domain with a high risk of bias and no domain with high applicability concerns; medium/moderate-quality study: a study that had domain with an unclear risk of bias or domain with unclear applicability concerns; low-quality study: a study that had a domain with a high risk of bias and domain with high applicability concerns
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BMC Infectious Diseases

ISSN: 1471-2334

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