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Table 2 Pooled Summary Estimates of All Studies

From: Diagnostic accuracy of in-house real-time PCR assay for Mycobacterium tuberculosis: a systematic review and meta-analysis

Accuracy Measure

Pooled summary measurea (95% CI)

P value for heterogeneityb

Sensitivity

0.96 (0.95–0.96)

< 0.001

Specificity

0.92 (0.90–0.93)

< 0.001

Positive Likelihood Ratio (LR+)

16.90 (7.22–39.56)

< 0.001

Negative Likelihood Ratio (LR-)

0.11 (0.06–0.18)

< 0.001

Diagnostic Odds Ratio (DOR)

192.96 (68.46–543.90)

< 0.001

  1. aRandom effects model
  2. bChi-square or Fisher’s exact test for heterogeneity