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Table 2 Campylobacter PCR positive-culture negative vs Campylobacter PCR positive-culture positive

From: Experiences from multiplex PCR diagnostics of faeces in hospitalised patients: clinical significance of Enteropathogenic Escherichia coli (EPEC) and culture negative campylobacter

Multiplex PCR result PCR positive-culture negative
N = 55 b
PCR positive-culture positive
N = 114
Campylobacter detected(all)
N = 169
Sex (male) [n (%)] 29 (53) 58 (51) 87 (51)
Age years [mean(SD)] 61 (21) 50 (16) 53 (19)
Other characteristics [%, (95% CI)]
 Ongoing antibiotic treatment 24 (13–37) 2.6 (0.5–7.5) 9.5 (5.5–15)
 Co-infection 18 (9.1–31) 1.7 (0.21–6.1) 7.1 (3.7–12)
 No diarrhoea 9.0 (3.0–20) 0.88 (0.02–4.8) 4.7 (2.7–9.9)
 Ongoing chemotherapy 5.4 (1.1–15) 2.6 (0.54–7.5) 3.5 (1.3–7.6)
 Travel associated 16 (7.8–29) 45 (35–54) 35 (28–43)
Clinical diagnosis [%, (95% CI)]
 Clinical non-infectious cause of diarrhoea 48 (34–63) 4.4 (1.4–10) 17 (11–23)a
  1. aA total of 6 patients did not present with diarrhoea and are excluded from these analyses
  2. b47 of 55 were sequenced as various Campylobacter spp., 29 as Campylobacter concisus (see Fig. 2)