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Table 4 Proportions of antimicrobial resistance among Enterobacteriaceae that were most frequently isolated from bloodstream infections

From: Bloodstream infections caused by multidrug-resistant gram-negative bacteria: epidemiological, clinical and microbiological features

 

Escherichia coli

(n = 50)

Klebsiella pneumoniae

(n = 50)

Serratia marcescens

(n = 50)

Enterobacter cloacae (n = 13)

Antimicrobial drug

No. of isolates

% resistant*

No. of isolates

% resistant*

No. of isolates

% resistant*

No. of isolates

% resistant*

Amikacin

1

2.0

1

6.7

Amp-Sul

28

56.0

31

62.0

15

100

13

100

Pip-Tazo

5**

10.0**

21

52.0

1

6.7

3

23.1

Ceftriaxone

10

20.0

25

50.0

NA

NA

NA

NA

Ceftazidime

10

20.0

25

50.0

NA

NA

Cefepime

10

20.0

25

50.0

1

6.7

3

23.1

Cefuroxime

12

24.0

26

52.0

NA

NA

NA

NA

Imipenem

2

4.0

5

10.0

-∆∆

-∆∆

1

7.7

Meropenem

1

2.0

5

10.0

1

7.7

Ertapenem

1

2.0

5+

10.0+

1

6.7

2

15.4

Ciprofloxacin

15

30.0

23

46.0

1§

6.7§

5

38.5

Gentamicin

5***

10.0***

14

28.0

3

23.1

Polymyxin

1

2.0

15§§

100§§

4

30.8

Tigecycline

4

8.0

1Ω

6.7 Ω

1 Ω Ω

7.7 Ω Ω

  1. *Considered resistant or intermediary profile;** Just 1 isolate of E. coli was not tested against piperacillin-tazobactam; *** Just 1 isolate of E. coli was not tested against gentamicin; +just 1 isolate of K. pneumoniae was not tested against ertapenem; 7 isolates of K. pneumoniae were not tested against tigecycline; ∆∆2 isolates of S. marcescens were not tested against imipenem; §2 isolates of S. marcescens were not tested against ciprofloxacin; §§S. marcescens is intrinsically resistant to polymyxin; Ω 1 isolate of S. marcescens were not tested against tigecycline; Ω Ω 3 isolates of E. cloacae were not tested against tigecycline; NA- Not applicable; (−) no resistant microbial isolates