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Table 3 Prevalence of latent tuberculosis infection and active tuberculosis disease among diabetic compared to non-diabetic adultsa

From: Interaction of nutritional status and diabetes on active and latent tuberculosis: a cross-sectional analysis

 

LTBI (n = 1113)

TB (n = 2032)

n (%)

PR (95% CI)

aPR (95% CI)b

n (%)

PR (95% CI)

aPR (95% CI)b

No history of diabetes

561/1044 (53.7)

1.00 (Referent)

1.00 (Referent)

623/1667 (37.4)

1.00 (Referent)

1.00 (Referent)

Prior diabetes diagnosis

44/69 (63.8)

1.24 (1.04, 1.48)

1.20 (0.99, 1.45)

296/365 (81.1)

3.83 (2.01, 7.30)

2.13 (1.95, 2.33)

Sensitivity analyses

 RBG < 200

553/1019 (54.2)

1.00 (Referent)

1.00 (Referent)

576/1595 (36.1)

1.00 (Referent)

1.00 (Referent)

 RBG ≥ 200 or prior diabetes diagnosis

52/94 (55.3)

1.04 (0.86, 1.25)

1.00 (0.82, 1.21)

343/437 (78.5)

2.17 (1.90, 2.48)

2.06 (1.90, 2.23)

 RBG < 140

517/928 (55.7)

1.00 (Referent)

1.00 (Referent)

440/1368 (32.2)

1.00 (Referent)

1.00 (Referent)

 RBG ≥ 200 or prior diabetes diagnosis

52/94 (55.3)

1.01 (0.84, 1.22)

0.97 (0.80, 1.18)

343/437 (78.5)

2.47 (2.25, 2.71)

2.19 (2.00, 2.39)

  1. aPR adjusted prevalence ratio, CI confidence interval, LTBI latent tuberculosis infection, PR prevalence ratio, RBG random blood glucose (mg/dL), TB tuberculosis
  2. a All models account for clustering at the family-level with an exchangeable correlation matrix. For LTBI, the referent group is LTBI-negative household contacts. For TB, the reference group is all household contacts
  3. b Adjusted for age, sex, body mass index category, smoking, and hazardous alcohol use