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Table 3 Prevalence of latent tuberculosis infection and active tuberculosis disease among diabetic compared to non-diabetic adultsa

From: Interaction of nutritional status and diabetes on active and latent tuberculosis: a cross-sectional analysis

  LTBI (n = 1113) TB (n = 2032)
n (%) PR (95% CI) aPR (95% CI)b n (%) PR (95% CI) aPR (95% CI)b
No history of diabetes 561/1044 (53.7) 1.00 (Referent) 1.00 (Referent) 623/1667 (37.4) 1.00 (Referent) 1.00 (Referent)
Prior diabetes diagnosis 44/69 (63.8) 1.24 (1.04, 1.48) 1.20 (0.99, 1.45) 296/365 (81.1) 3.83 (2.01, 7.30) 2.13 (1.95, 2.33)
Sensitivity analyses
 RBG < 200 553/1019 (54.2) 1.00 (Referent) 1.00 (Referent) 576/1595 (36.1) 1.00 (Referent) 1.00 (Referent)
 RBG ≥ 200 or prior diabetes diagnosis 52/94 (55.3) 1.04 (0.86, 1.25) 1.00 (0.82, 1.21) 343/437 (78.5) 2.17 (1.90, 2.48) 2.06 (1.90, 2.23)
 RBG < 140 517/928 (55.7) 1.00 (Referent) 1.00 (Referent) 440/1368 (32.2) 1.00 (Referent) 1.00 (Referent)
 RBG ≥ 200 or prior diabetes diagnosis 52/94 (55.3) 1.01 (0.84, 1.22) 0.97 (0.80, 1.18) 343/437 (78.5) 2.47 (2.25, 2.71) 2.19 (2.00, 2.39)
  1. aPR adjusted prevalence ratio, CI confidence interval, LTBI latent tuberculosis infection, PR prevalence ratio, RBG random blood glucose (mg/dL), TB tuberculosis
  2. a All models account for clustering at the family-level with an exchangeable correlation matrix. For LTBI, the referent group is LTBI-negative household contacts. For TB, the reference group is all household contacts
  3. b Adjusted for age, sex, body mass index category, smoking, and hazardous alcohol use