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Table 2 Factors associated with active TB incidence in follow-up individuals

From: The association between tuberculin skin test result and active tuberculosis risk of college students in Beijing, China: a retrospective cohort study

  # of individuals TB events/follow-up person-years IRa(95% CI) P for chi-square test Univariate Cox regression Multivariate Cox regression
HR (95% CI) P value Adjusted HR(95% CI) P value
Sex 0.01  
 Female 30941 5/61881 8.08 (2.62~18.86)   Reference Reference
 Male 36351 21/72694 28.89 (17.88~44.17) 3.576 (1.348~9.483) 0.01 3.593 (1.354~9.537) 0.01
Ethnicity 0.86  
 Han 60086 23/120164 19.14 (12.12~28.73)   Reference Reference
 Others 7206 3/14411 20.82 (4.29~60.85) 1.088 (0.3266~3.622) 0.89  
Region 0.21  
 East 33692 14/67377 20.78 (11.35~34.87)   Reference Reference
 Middle 17069 3/34138 8.79 (1.81~25.69) 0.423 (0.121~1.472) 0.17  
 West 16531 9/33060 27.22 (12.44~51.70) 1.310 (0.567~3.027) 0.52
TST response (induration size, mm) < 0.001  
 0~4 51963 13/103923 12.51 (6.65~21.40)   Reference Reference
 5~9 7308 2/14615 13.68 (1.66~49.44) 1.094 (0.247~4.848) 0.91 1.094 (0.247~4.846) 0.91
 10~14 4217 4/8431 47.44 (12.90~121.50) 3.794 (1.237~11.635) 0.02 3.644 (1.188~11.179) 0.02
 15~19 2918 5/5834 85.70 (27.77~200.03) 6.853 (2.443~19.223) < 0.001 6.832 (2.436~19.163) < 0.001
  ≥ 20 886 2/1772 112.87 (13.66~407.79) 9.032 (2.038~40.025) 0.004 9.768 (2.203~43.315) 0.003
  1. IR Incidence rate, HR Hazard ratio, CI Confidence interval
  2. a Per 100 000 person years