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Table 3 Antibiogram of Leishmania spp. Resistance at Varying Concentrations of Amphotericin B and Fluconazole

From: Susceptibility testing of Leishmania spp. against amphotericin B and fluconazole using the Sensititre™ YeastOne™ YO9 platform

Species

Total Number of Isolates

Amphotericin B (μg/mL)

Fluconazole (μg/mL)

0.12

0.25

0.5

1

≥256

Old World

L. donovani

3

3 (100%)

0 (0%)

0 (0%)

0 (0%)

3 (100%)

L. infantum

8

2 (25%)

1 (12.5%)

0 (0%)

0 (0%)

8 (100%)

L. major

4

4 (100%)

3 (75%)

0 (0%)

0 (0%)

4 (100%)

L. tropica

9

9 (100%)

0 (0%)

0 (0%)

0 (0%)

9 (100%)

New World

L. amazonensis

3

3 (100%)

2 (66.6%)

1 (33.3%)

0 (0%)

3 (100%)

L. chagasi

3

3 (100%)

1 (33.3%)

0 (0%)

0 (0%)

3 (100%)

L. mexicana

3

3 (100%)

1 (33.35%)

0 (0%)

0 (0%)

3 (100%)

L. V. braziliensis

6

6 (100%)

3 (50%)

0 (0%)

0 (0%)

6 (100%)

L. V. guyanensis

4

2 (50%)

1 (25%)

0 (0%)

0 (0%)

4 (100%)

L. V. panamensis

18

7 (39%)

6 (40%)

0 (0%)

0 (0%)

18 (100%)