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Table 3 Comparison of the performance characteristics of two methods for detection of macrolide resistance mutations at 23S rRNA

From: Allele-specific real-time PCR testing for minor macrolide-resistant Mycoplasma Pneumoniae

Genotypes Method
ASPCR Nested PCR + sequencing
Total 178 178
M. pneumoniae positive (no, %) 164 153
Resistance mutations 149 110
A2063G 38 109
A2063G + WT 53 0
A2064G + WT 5 0
A2063G + A2064G + WT 43 0
A2063G + A2064G 10 0
A2064G 0 1
WT 15 43
Negative 14 25
  1. WT (wild-type): no macrolide resistance mutation detected