Severe oxidative stress in sickle cell disease patients with uncomplicated Plasmodium falciparum malaria in Kampala, Uganda

Table 4 MDA and other Biomarkers of Oxidative stress

Biomarker	GSH	GPx	CAT
SCD Malaria n	51	51	51
Pearson r	−0.2500	0.2893	−0.1456
P value (two-tailed)	0.0769	0.0395	0.3081
R²	0.06249	0.08369	0.02119
Malaria
Pearson r	0.01729	0.07464	0.1865
P value (two-tailed)	0.9013	0.5917	0.1769
R²	0.0002988	0.005571	0.03479
SCD control
Pearson r	−0.05931	−0.3836	0.07885
P value (two-tailed)	0.6793	0.0055	0.5823
R²	0.003518	0.1472	0.006217
Healthy control
Pearson r	0.01596	0.0278	−0.01898
P value (two-tailed)	0.9115	0.8464	0.8948
R²	0.0002547	0.0007729	0.0003601

MDA malondialdehyde, GSH reduced glutathione, GPx Glutathione peroxidase (a negative r value that is significant), CAT catalase

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